João C. Ferreira

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The role of exercise training (ET) on cardiac renin-angiotensin system (RAS) was investigated in 3–5 month-old mice lacking α2A- and α2C-adrenoceptors (α2A/α2CARKO) that present heart failure (HF)(More)
Sympathetic hyperactivity (SH) and renin angiotensin system (RAS) activation are commonly associated with heart failure (HF), even though the relative contribution of these factors to the cardiac(More)
The cellular mechanisms of positive effects associated with aerobic exercise training on overall intrinsic skeletal muscle changes in heart failure (HF) remain unclear. We investigated potential Ca2+(More)
Heart failure is a common endpoint for many forms of cardiovascular disease and a significant cause of morbidity and mortality. Chronic neurohumoral excitation (i.e., sympathetic hyperactivity) has(More)