João Borges Fortes Filho

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OBJECTIVES This study evaluated the incidence and risk factors for severe retinopathy of prematurity (ROP) in babies <1000 g at Porto Alegre, Brazil. METHODS Prospective cohort study including premature children with birth weight ≤1000 g was conducted. Main outcome was the occurrence of severe ROP needing treatment. RESULTS A total of 157 infants were(More)
OBJECTIVE Retinopathy of prematurity (ROP) is the leading cause of childhood blindness in most developed countries. This study aimed to verify ROP prevalence among all very low birth weight (VLBW) preterm infants admitted to a level-3 teaching hospital in Porto Alegre, Rio Grande do Sul, Brazil. METHODS Institutional cross-sectional study of 407 premature(More)
OBJECTIVE To analyze prevalence and risk factors for retinopathy of prematurity (ROP) among preterm infants born small for gestational age (SGA) and appropriate for gestational age (AGA). METHODS A prospective cohort study included preterm infants with birth weight (BW) < or = 1,500 grams and gestational age (GA) < or = 32 weeks, divided into two groups:(More)
PURPOSE The aim of the study was to assess the outcomes of severe retinopathy of prematurity (ROP) in zone I or posterior zone II treated with intravitreal ranibizumab (IVR) as monotherapy or combined treatment with laser photocoagulation. METHODS This is a retrospective study analyzing clinical records of the included patients. Patients were divided into(More)
BACKGROUND To report a case series of nine patients presenting with leukocoria without lens opacification or retrolental abnormalities and to propose a novel classification for leukocoria. METHODS An institutional and retrospective study including a case series of patients assisted in the Congenital Cataract Section of Federal University of São Paulo,(More)
PURPOSE To prospectively study the association of high cytokine plasma levels with later development of retinopathy of prematurity (ROP) in preterm infants with early-onset sepsis to assess a laboratory test to detect ROP. METHODS A prospective cohort study was conducted of preterm infants with clinical early-onset sepsis whose birth weight (BW) was ≤1500(More)
Retinopathy of prematurity (ROP) is related to oxygen-regulated vascular endothelial growth factor and to insulin-like growth factor-I. After premature birth, supplemental oxygen induces a retinal hyperoxic condition with vasoconstriction and to a definitive interruption of retinal vasculogenesis. Peripheral ischemia may stimulate retinal neovascularization(More)
BACKGROUND Improved survival of preterm neonates has increased the incidence of retinopathy of prematurity (ROP) in many middle-income countries. AIM This study aimed to verify the main risk factors for the development of ROP according to different gestational age (GA) groups. METHODS A prospective cohort study including infants weighing < or =1,500 g(More)
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