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  • Elizabeth Soares Fernandes, Giselle Fazzioni Passos, +5 authors João B. Calixto
  • Chemistry, Medicine
  • European journal of pharmacology
  • 2007 (First Publication: 1 August 2007)
  • This study evaluated the anti-inflammatory properties of two sesquiterpenes isolated from Cordia verbenacea's essential oil, alpha-humulene and (-)-trans-caryophyllene. Our results revealed that oralContinue Reading
  • João B. Calixto, Rodrigo Medeiros, Elizabeth Soares Fernandes, Juliano Ferreira, Daniela de Almeida Cabrini, Maria M Campos
  • Medicine, Chemistry
  • British journal of pharmacology
  • 2004 (First Publication: 1 December 2004)
  • Kinins are a family of peptides implicated in several pathophysiological events. Most of their effects are likely mediated by the activation of two G-protein-coupled receptors: B(1) and B(2). WhereasContinue Reading
  • Angelo Oscar da Rosa, Jaime Lin, João B. Calixto, Adair R. S. Santos, Ana Lúcia S. Rodrigues
  • Psychology, Medicine
  • Behavioural Brain Research
  • 2003 (First Publication: 1 September 2003)
  • This study investigated the involvement of NMDA receptors and the L-arginine-nitric oxide (NO) pathway in the antidepressant-like effects of zinc in the forced swimming test (FST). The immobilityContinue Reading
  • Raquel Maria Teixeira, A R Santos, S. J. Alvaro Ribeiro, João B. Calixto, Giles Alexander Rae, Thereza Christina Monteiro de Lima
  • Chemistry, Medicine
  • European journal of pharmacology
  • 1996 (First Publication: 1 September 1996)
  • This study assessed the effects of intracerebroventricular administration of selective agonists and antagonists for tachykinin NK1 and NK2 receptors on performance of mice in the elevated plus-maze,Continue Reading
  • Andréa D. E. Zomkowski, L. Hammes, Jaime Lin, João B. Calixto, Adair R. S. Santos, Ana Lúcia S. Rodrigues
  • Biology, Medicine
  • Neuroreport
  • 2002 (First Publication: 1 March 2002)
  • Agmatine produces an antidepressant-like effect when assessed in the forced swimming test (FST) and in the tail suspension test (TST) in mice (dose range 0.01-50 mg/kg, i.p.), without accompanyingContinue Reading
  • João B. Calixto, A R Santos, Valdir Cechinel Filho, Rosendo Augusto Yunes
  • Medicine, Biology
  • Medicinal research reviews
  • 1998 (First Publication: 1 July 1998)
  • The plants of the genus Phyllanthus (Euphorbiaceae) are widely distributed in most tropical and subtropical countries, and have long been used in folk medicine to treat kidney and urinary bladderContinue Reading