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Background Functional heterogeneity in the tumor necrosis factor α (TNF-α) gene may be responsible for the TNF-α response in infectious and autoimmune diseases. Recently, the TNF-238 promoter… (More)
Background and Objectives Vitamin D has suppressive effects on autoimmune diseases, such as rheumatoid arthritis (RA). Within these diseases, T-helper-17 (Th17) cells have been implicated to play a… (More)
Multiple genetic factors contribute to susceptibility to rheumatoid arthritis (RA). The extent of variability in disease presentation in RA may be related to genetic heterogeneity. In this study we… (More)