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Quality of life in Chinese home-based advanced cancer patients: does awareness of cancer diagnosis matter?
- Xiaoping Fan, Hua Huang, Qiong Luo, Jiying Zhou, G. Tan, Na Yong
- MedicineJournal of palliative medicine
- 17 October 2011
The principal finding of this study demonstrated that patients who did not have knowledge of their diagnosis exhibited better physical and emotional QOL compared with those who had knowledge of the diagnosis.
Microglial NLRP3 inflammasome activation mediates IL-1β release and contributes to central sensitization in a recurrent nitroglycerin-induced migraine model
Results indicate that NLRP3 activation in the TNC participates in the microglial-neuronal signal by mediating the inflammatory response, which contributes to the central sensitization observed in CM.
Microglia P2X4R-BDNF signalling contributes to central sensitization in a recurrent nitroglycerin-induced chronic migraine model
The results indicated that the P2X4R contributes to the central sensitization of CM by releasing BDNF and promoting TNC neuronal hyper-excitability and blocking microglia P2x4R-BDNF signalling may have an effect on the prevention of migraine chronification.
Prevalence and risk factors for depression and anxiety among outpatient migraineurs in mainland China
It is demonstrated that depression and anxiety comorbidity in mainland Chinese migraineurs are also common, and several risk factors were identified that may provide predictive value.
Microglia P2X4 receptor contributes to central sensitization following recurrent nitroglycerin stimulation
It is speculated that the P2X4R may be implicated in the microglia-neuronal signal in the TNC, which contributes to the central sensitization of CM, and blocking microglian activation may have an effect on the prevention of migraine chronification.
Replication of Migraine GWAS Susceptibility Loci in Chinese Han Population
This work investigated the 3 genetic variants rs2651899, rs10166942, and rs11172113 for their association with migraine in the Chinese Han population and found no evidence that these variants cause migraine in other populations.
P2X4-receptor participates in EAAT3 regulation via BDNF-TrkB signaling in a model of trigeminal allodynia
Data indicate that microglial P2X4R is involved in the regulation of excitatory amino acid transporter 3 via brain-derived neurotrophic factor-tyrosine receptor kinase B signaling following repeated inflammatory dural stimulation, and may play a role in the pathogenesis of migraine chronicity.
Prevalence and predictive factors for poor sleep quality among migraineurs in a tertiary hospital headache clinic
- Zhou Zhu, Xiaoping Fan, Xuelian Li, G. Tan, Lixue Chen, Jiying Zhou
- Psychology, MedicineActa Neurologica Belgica
- 1 September 2013
It was found that most migraineurs did not adopt treatment for their poor sleep quality and the primary factors that predicted poorSleep quality included the migraine history and comorbidity with anxiety and/or depression.
Classification and clinical features of headache patients: an outpatient clinic study from China
- Yunfeng Wang, Jiying Zhou, Bo-wen Liu
- Medicine, PsychologyThe Journal of Headache and Pain
- 9 July 2011
In outpatient headaches, more attention should been given to headache intensity and duration of headache history for migraine patients, while more attention to headache frequency should be given for the TTH ones.
NR2B-Tyr phosphorylation regulates synaptic plasticity in central sensitization in a chronic migraine rat model
The inhibition of NR2B tyrosine phosphorylation has a protective effect on threshold dysfunction and migraine attacks through the regulation of synaptic plasticity in central sensitization in a CM rat model.