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Microglial NLRP3 inflammasome activation mediates IL-1β release and contributes to central sensitization in a recurrent nitroglycerin-induced migraine model
TLDR
Results indicate that NLRP3 activation in the TNC participates in the microglial-neuronal signal by mediating the inflammatory response, which contributes to the central sensitization observed in CM. Expand
Classification and clinical features of headache patients: an outpatient clinic study from China
TLDR
In outpatient headaches, more attention should been given to headache intensity and duration of headache history for migraine patients, while more attention to headache frequency should be given for the TTH ones. Expand
Microglia P2X4R-BDNF signalling contributes to central sensitization in a recurrent nitroglycerin-induced chronic migraine model
TLDR
The results indicated that the P2X4R contributes to the central sensitization of CM by releasing BDNF and promoting TNC neuronal hyper-excitability and blocking microglia P2x4R-BDNF signalling may have an effect on the prevention of migraine chronification. Expand
Replication of Migraine GWAS Susceptibility Loci in Chinese Han Population
TLDR
This work investigated the 3 genetic variants rs2651899, rs10166942, and rs11172113 for their association with migraine in the Chinese Han population and found no evidence that these variants cause migraine in other populations. Expand
Sporadic Hemiplegic Migraine With Permanent Neurological Deficits
TLDR
The case of a patient with permanent impairments because of hemiplegic migraine despite normalization of associated brain magnetic resonance imaging abnormalities, suggesting the need to consider aggressive prophylactic therapy for patients with recurrent hemipLegic migraine attacks. Expand
Prevalence and predictive factors for poor sleep quality among migraineurs in a tertiary hospital headache clinic
TLDR
It was found that most migraineurs did not adopt treatment for their poor sleep quality and the primary factors that predicted poorSleep quality included the migraine history and comorbidity with anxiety and/or depression. Expand
EPC mobilization after erythropoietin treatment in acute ST-elevation myocardial infarction: the REVEAL EPC substudy
TLDR
High-dose (≥30,000 U) EPO may mobilize EPCs at 48–72 h, and baseline EPC levels may be inversely associated with infarct size, while local whole cell cryopreservation and central EPC analysis in the context of a multicenter randomized trial is feasible but challenging. Expand
Prevalence and risk factors for depression and anxiety among outpatient migraineurs in mainland China
TLDR
It is demonstrated that depression and anxiety comorbidity in mainland Chinese migraineurs are also common, and several risk factors were identified that may provide predictive value. Expand
Diagnosis and treatment status of migraine: A clinic-based study in China
TLDR
Migraine is the most common headache disorder in the neurological clinic and it remains underrecognized and undertreated in China. Expand
Headache Care in China
TLDR
A review summarizes the outcomes of the epidemiological survey and the progress of clinical and basic research in China, describes the present situation in terms of headache diagnosis and treatment, and discusses the future of headache care in China. Expand
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