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Chlamydia pneumoniae IgA titres and coronary heart disease: prospective study and meta-analysis Our synthesis of the available evidence from 10 long-term prospective studies in approximately general populations, involving a total of 2283 cases of non-fatal myocardial infarc-tion or coronary heart disease death and 7143 controls, yielded a combined odds(More)
In this paper, without assuming the boundedness, monotonicity and differentiability of the activation functions, we present new conditions ensuring existence, uniqueness, and global asymptotical stability of the equilibrium point of Hopfield neural network models with fixed time delays or distributed time delays. The results are applicable to both symmetric(More)
OBJECTIVE Concentration of extracellular calcium ([Ca(2+)](o)) in the central nervous system decreases substantially in different conditions. It results in facilitating neuronal excitability. The goal of this study is to examine the mechanisms of enhanced neuronal excitation in low [Ca(2+)](o) in order to provide new clues to treat the hyperexcitability(More)
Mesenchymal stem cells (MSCs) are multipotent cells which reside in many tissues and can give rise to multiple lineages including bone, cartilage and adipose. Although MSCs have attracted significant attention for basic and translational research, primary MSCs have limited life span in culture which hampers MSCs' broader applications. Here, we investigate(More)
Sirtuin 1 (SIRT1), a NAD+-dependent class III histone deacetylase, participates in regulating cellular apoptosis, senescence and metabolism by deacetylating histones and multiple transcription factors. In this study, we aimed to determine the effect of SIRT1 on the apoptosis of vascular adventitial fibroblasts (VAFs) and related signaling pathways. SIRT1(More)
OBJECTIVE Progenitor cell-based cardiomyocyte regeneration holds great promise of repairing an injured heart. Although cardiomyogenic differentiation has been reported for a variety of progenitor cell types, the biological factors that regulate effective cardiomyogenesis remain largely undefined. Primary cardiomyogenic progenitors (CPs) have a limited life(More)