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Following a Letter to the Editor from Dr Zeiger concerning my recent article in Mutagenesis, 10, 447—448, I would like to clarify, where possible, the points raised. The use of the 'known carcinogens/mutagens' and 'known non-carcinogens/ mutagens' was: (i) to show that the assay would produce qualitative increases with 'known carcinogens/mutagens', and (ii)(More)
In this paper, without assuming the boundedness, monotonicity and differentiability of the activation functions, we present new conditions ensuring existence, uniqueness, and global asymptotical stability of the equilibrium point of Hopfield neural network models with fixed time delays or distributed time delays. The results are applicable to both symmetric(More)
Mesenchymal stem cells (MSCs) are multipotent cells which reside in many tissues and can give rise to multiple lineages including bone, cartilage and adipose. Although MSCs have attracted significant attention for basic and translational research, primary MSCs have limited life span in culture which hampers MSCs' broader applications. Here, we investigate(More)
Sirtuin 1 (SIRT1), a NAD+-dependent class III histone deacetylase, participates in regulating cellular apoptosis, senescence and metabolism by deacetylating histones and multiple transcription factors. In this study, we aimed to determine the effect of SIRT1 on the apoptosis of vascular adventitial fibroblasts (VAFs) and related signaling pathways. SIRT1(More)
Mesenchymal stem cells (MSCs) are multipotent progenitors, which give rise to several lineages, including bone, cartilage and fat. Epidermal growth factor (EGF) stimulates cell growth, proliferation and differentiation. EGF acts by binding with high affinity to epidermal growth factor receptor (EGFR) on the cell surface and stimulating the intrinsic protein(More)
In this paper, the existence and uniqueness of the equilibrium point and absolute stability of a class of neural networks with partially Lipschitz continuous activation functions are investigated. The neural networks contain both variable and unbounded delays. Using the matrix property, a necessary and sufficient condition for the existence and uniqueness(More)