Jiye Huang

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Oral diseases are major public health problems that impact people from early childhood. However, children's oral hygiene in China remains a severe problem due to inadequate education on oral hygiene behavior and parents' lack of knowledge about their childrens' dental condition. To address these problems, we propose DAYA, a system consisting of a(More)
A novel scaffold derived from l-SPD with a substituted thiophene group in the D ring were designed, synthesized, and evaluated for their binding affinities at dopamine (D1, D2 and D3) and serotonin (5-HT1A and 5-HT2A) receptors. Most of the tetracyclic compounds exhibited higher affinities for D2 and 5-HT1A receptors than l-SPD, while compound 23 e showed(More)
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