Jitamanyu Chakrabarty

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A stability-indicating RP-HPLC method has been developed and validated for the simultaneous determination of phenoxyethanol (PE), methylparaben (MP), propylparaben (PP), mometasone furoate (MF), and tazarotene (TA) in topical pharmaceutical dosage formulation. The desired chromatographic separation was achieved on the Waters X-Bridge™ C18 (50×4.6mm, 3.5μ)(More)
A sensitive, fast, and stability-indicating isocratic reverse-phase ultra-performance liquid chromatography method was developed and validated for quantitative simultaneous determination of sodium methylparaben, sodium propylparaben and ketorolac tromethamine in topical dosage forms. Separation of all peaks was achieved by using acquity ethylene bridged(More)
In search of specific label-free biomarkers for differentiation of two oral lesions, namely oral leukoplakia (OLK) and oral squamous-cell carcinoma (OSCC), Fourier-transform infrared (FTIR) spectroscopy was performed on paraffin-embedded tissue sections from 47 human subjects (eight normal (NOM), 16 OLK, and 23 OSCC). Difference between mean spectra (DBMS),(More)
A simple, specific, accurate and stability-indicating RP-HPLC method was developed and validated for determination of related substances in Tretinoin topical pharmaceutical formulation. Chromatographic separation was achieved on Hypersil BDS C18 250 × 4.6mm, 5μ column as stationary phase while mobile phase A was buffer, (Buffer=Water : Glacial acetic acid,(More)
Application of microalgae for defluoridation has gained interest in recent years. In the present study, bioremediation of fluoride using living cyanobacteria, Starria zimbabweensis, collected from wastewater of coke-oven effluent treatment plant, Durgapur, India, has been investigated. Initially, the cyanobacterial strain was grown in BG11 medium at 25°C,(More)
A simple precise NP-HPLC method development and validation for simultaneous determination of Betamethasone Dipropionate and Calcipotriene in topical formulation. Chromatographic separation of drug was achieved on Inertsil Silica 100Ao (250×4.6mm, 3μ) column with mobile phase A n-Hexane, tetrahydrofuran and Ethanol in the ratio 95:5:2 v/v/v, respectively as(More)
The objective of the current study was to establish a validated stability-indicating, high-performance liquid chromatographic method to determine the purity of benzoyl peroxide (BPO) and adapalene (ADP) in the presence of its impurities, forced degradation products, and placebo in pharmaceutical dosage forms. The desired chromatographic separation was(More)
A stability-indicating RP-HPLC method has been developed and validated for the simultaneous determination of methylparaben (MP), propylparaben (PP), diethylamino hydroxybenzoyl hexyl benzoate (DAHHB), and octinoxate (OCT) in topical pharmaceutical formulation. The desired chromatographic separation was achieved on the Kinetex(TM) C18 (250 × 4.6 mm, 5 μm)(More)
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