Jisí Hrebícek

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Obesity and diabetes mellitus type 2 belong among the most frequent illnesses and are categorized among the dominant risk factors for cardiovascular disease in all developed countries. There is a causal relation between insulin resistance and the origin of these risk factors of the cardiovascular morbidity and mortality. Numerous studies have attemted to(More)
Tumor necrosis factor alpha (TNFalpha) and leptin concentrations were determined in the abdominal subcutaneous and visceral (omental) adipose tissue of patients undergoing elective open-abdominal surgery and compared with their body mass index. The concentration of leptin did not differ significantly between women and men, being high in subcutaneous fat(More)
This review deals with general mechanisms of peroxisome proliferator-activated receptors (PPARs) functions, describes the mode of action of various PPAR subtypes in different tissues and their participation in transcription of genes governing lipid and glucose homeostasis. The hypothetic role of free fatty acids in mediating metabolic effects of PPARs,(More)
Strategic decision-making for dealing with municipal solid waste is a problem currently exercising the minds of many Member States throughout the European Union. This paper is devoted to environmental–economic modelling of the strategic developments in Municipal Solid Waste Management Systems at the Czech Republic. It was created by the authors for the(More)
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