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Rapid and simple detection of Ebola virus by reverse transcription-loop-mediated isothermal amplification.

• Yohei Kurosaki, Ayato Takada, +5 authors Jiro Yasuda
• Journal of virological methods
• 2007

Ebola virus (EBOV) causes severe hemorrhagic fever in humans and nonhuman primates with high mortality rates. Rapid identification of the virus is required to prevent spread of the infection. In this… (More)

The penta-EF-hand protein ALG-2 interacts directly with the ESCRT-I component TSG101, and Ca2+-dependently co-localizes to aberrant endosomes with dominant-negative AAA ATPase SKD1/Vps4B.

• Keiichi Katoh, Hidenori Suzuki, +4 authors Masatoshi Maki
• The Biochemical journal
• 2005

ALG-2 (apoptosis-linked gene 2) is a Ca2+-binding protein that belongs to the PEF (penta-EF-hand) protein family. Alix (ALG-2-interacting protein X)/AIP1 (ALG-2-interacting protein 1), one of its… (More)

Dimerization of Tetherin Is Not Essential for Its Antiviral Activity against Lassa and Marburg Viruses

• Toshie Sakuma, Akira Sakurai, Jiro Yasuda
• PloS one
• 2009

Tetherin (also known as BST2, CD317 or HM1.24) has recently been reported to inhibit a wide range of viruses. However, the antiviral mechanism of action of tetherin has not been determined. Both ends… (More)

Development and Evaluation of Reverse Transcription-Loop-Mediated Isothermal Amplification (RT-LAMP) Assay Coupled with a Portable Device for Rapid Diagnosis of Ebola Virus Disease in Guinea

• Yohei Kurosaki, N’faly Magassouba, +6 authors Thomas W. Geisbert
• PLoS neglected tropical diseases
• 2016

Given the current absence of specific drugs or vaccines for Ebola virus disease (EVD), rapid, sensitive, and reliable diagnostic methods are required to stem the transmission chain of the disease. We… (More)

Cloning and Characterization of the Antiviral Activity of Feline Tetherin/BST-2

• Aiko Fukuma, Masumi Abe, Yuko Morikawa, Takayuki Miyazawa, Jiro Yasuda
• PloS one
• 2011

Human Tetherin/BST-2 has recently been identified as a cellular antiviral factor that blocks the release of various enveloped viruses. In this study, we cloned a cDNA fragment encoding a feline… (More)

Characterization of the catalytic activity of the gamma-phage lysin, PlyG, specific for Bacillus anthracis.

• Hitomi S. Kikkawa, Takuya Ueda, Shin-ichi Suzuki, Jiro Yasuda
• FEMS microbiology letters
• 2008

Bacillus anthracis causes anthrax, a lethal disease affecting humans that has attracted attention due to its bioterrorism potential. PlyG is a lysin of gamma-phage, which specifically infects B.… (More)

Identification and Functional Analysis of Three Isoforms of Bovine BST-2

• Eri Takeda, So Nakagawa, Yuki Nakaya, Atsushi Tanaka, Takayuki Miyazawa, Jiro Yasuda
• PloS one
• 2012

Human BST-2 (hBST-2) has been identified as a cellular antiviral factor that blocks the release of various enveloped viruses. Orthologues of BST-2 have been identified in several species, including… (More)

Development and evaluation of a simple assay for Marburg virus detection using a reverse transcription-loop-mediated isothermal amplification method.

• Yohei Kurosaki, Allen Grolla, Aiko Fukuma, Heinz Feldmann, Jiro Yasuda
• Journal of clinical microbiology
• 2010

Marburg virus (MARV) causes a severe hemorrhagic fever in humans with a high mortality rate. The rapid and accurate identification of the virus is required to appropriately provide infection control… (More)

Taxonomic studies on the bacterial strains isolated from cases of "shirasu" food-poisoning (Pasteurella parahaemolytica) and related microorganisms.

• Takahiro Fujino, Toshio Miwatani, +9 authors Yutaka Tamura
• Biken journal
• 1965

Deployment of a Reverse Transcription Loop-Mediated Isothermal Amplification Test for Ebola Virus Surveillance in Remote Areas in Guinea.

• Yohei Kurosaki, N'faly Magassouba, +6 authors Jiro Yasuda
• The Journal of infectious diseases
• 2016

To strengthen the laboratory diagnostic capacity for Ebola virus disease (EVD) in the remote areas of Guinea, we deployed a mobile field laboratory and implemented reverse transcription loop-mediated… (More)

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