Jiri Zelenka

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BACKGROUND Atrial fibrillation is associated with higher mortality. Identification of causes of death and contemporary risk factors for all-cause mortality may guide interventions. METHODS AND RESULTS In the Rivaroxaban Once Daily Oral Direct Factor Xa Inhibition Compared with Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial(More)
Homeostasis of reactive oxygen species (ROS) in cardiomyocytes is critical for elucidation of normal heart physiology and pathology. Mitochondrial phospholipases A2 (mt-PLA2) have been previously suggested to be activated by ROS. Therefore, we have attempted to elucidate physiological role of such activation. We have found that function of a specific(More)
BACKGROUND Diabetic Goto Kakizaki (GK) rats represent an established model of type 2 diabetes that exhibit an onset of pancreatic islet (PI) pathology characterized by islet hypertrophy with a decreased number of insulin-secreting β-cells. Among the remaining β-cells, oxidative phosphorylation (OXPHOS) and consequently glucose-stimulated insulin secretion(More)
A new multiple index technique is presented for holographically generating contours of constant depth. With this technique it is possible for the first time to use the multiple index method for obtaining high contrast contours denoting small depth changes over large surfaces. The improved multiple index technique is compared with an analogous multiple(More)
The distribution and biological half-life of radiocaesium (137Cs) in broiler chickens after three oral applications (in course of 1 day at the age of 14 days) of artificially contaminated feed mixture were studied. There was a rapid uptake of the orally administered 137Cs (within a few hours) and also a rapid loss of 137Cs which varied in the different(More)
VoIP technology becomes more and more profitable and many people prefer this kind of connection instead of classic TDMA telecommunication network. Very helpful is a fact that with voice services becomes another related services like a video, a text or even a file transmission. These services are integrated both into simple software VoIP clients and hardware(More)
A study of the effects of photographic nonlinearities in recording coherent wavefronts is reported. Particular emphasis is placed on holography using the two-beam interferometry technique. A phenomenological model which provides the mathematical formulation for describing the effects of nonlinearities is described. The model includes a zero-memory(More)
Research on brown adipose tissue and its hallmark protein, mitochondrial uncoupling protein UCP1, has been conducted for half a century and has been traditionally studied in the Institute of Physiology (AS CR, Prague), likewise UCP2 residing in multiple tissues for the last two decades. Our group has significantly contributed to the elucidation of UCP(More)