Recent advances in the study of the CRISPR/Cas9 system have provided a precise and versatile approach for genome editing in various species. However, the applicability and efficiency of this method in large animal models, such as the goat, have not been extensively studied. Here, by co-injection of one-cell stage embryos with Cas9 mRNA and sgRNAs targeting… (More)
Blum integers (BL), which has extensively been used in the domain of cryptography, are integers with form p k1 q k2 , where p and q are different primes both ≡ 3 mod 4 and k 1 and k 2 are odd integers. These integers can be divided two types: 1) M = pq, 2) M = p k1 q k2 , where at least one of k 1 and k 2 is greater than 1. In , Bruce Schneier has… (More)
In this paper, the authors study binomial skew polynomial ring <i>A</i>. We can find a Gröbner basis of a two-sided ideal (as left ideal). Thus, we solve the question 2 in : Is it true that <i>A</i> has a decidable membership problem for finitely generated two-sided ideals?