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BACKGROUND To study the apoptosis-inducing effect of Tanshinone and its molecular mechanism on human lung cancer cells. METHODS Human lung cancer cell line (SPC-A-1) was treated in vitro with 0.5 mg/L Tanshinone IIA for five days, and the cells treated with all trans retinoic acid (RA) or DDP as controls. Changes in cell morphology, apoptotic index and(More)
BACKGROUND To explore the inhibiting effect and its molecular mechanism of Tanshione on human lung carcinoma cell line. METHODS Human lung adenocarcinoma cell line (SPC-A-1) was treated IN VITRO with 0.5 mug/mL Tanshinone IIA (Tan IIA) for five days, other equal cells were also treated with all transretinoic acid (RA) and DDP respectively as control.(More)
BACKGROUND To study the growth-inhibiting effect and its molecular mechanism of Tanshinone on human lung carcinoma cell line. METHODS Human lung adenocarcinoma cell line (SPC-A-1) was treated in vitro with 0.5μg/ml Tanshinone IIA for five days, and the cells treated with all trans retinoic acid (RA) and DDP as control. Changes in cell morphology,(More)
BACKGROUND It has been proved that Tanshinone has obvious anticancer effect, but its mechanisms of anticancer are still unknown. Anticancer Ketonon is complex antitumor drug which Tanshinone is combined with other anticancer elements. This study aims to explore the antineoplastic effects of Anticancer Ketonon on Lewis lung cancer and the mechanisms in mice.(More)
BACKGROUND The prevalence of lung cancer in the elder increases gradually recently, and lung cancer has become the main cause of cancer-related death. The aim of this study is to analyse the operative indication, complication, perioperative management and surgical measures, results and specificity for lung cancer in the elderly patients. METHODS One(More)
OBJECTIVE To compare thoracoscopic esophagectomy with traditional esophagectomy in radical mediastinal lymphadenectomy for esophageal cancer, and to explore the feasibility and safety of thoracoscopic mediastinal lymphadenectomy for esophagectomy. METHODS Clinical data associated with perioperation and mediastinal lymph nodes clearance of 304 patients(More)
BACKGROUND AND OBJECTIVE although widely adopted, there is lack of comparative data for patients undergoing lymph node dissection in radical surgery of lung cancer by video-assisted thoracoscopic surgery (VATS) vs conventional lateral incision surgery. The aim of this study is to compare the effects of lymph node dissection in radical surgery of lung cancer(More)
BACKGROUND To observe the growth-inhibiting effect of anticancer ketonon on A549 cell line and PLA-801D cell line and to explore its mechanism based on the antineoplastic effects of Tanshinon. METHODS A549 and PLA-801D cell lines were treated with anticancer ketonon by techniques of cell culture in vitro . The growth curves and dose-effect curves were(More)
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