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Polychlorinated biphenyls (PCBs) can severely interfere with multiple animals and human systems. To explore the molecular mechanisms underlying 2, 3', 4, 4', 5- pentachlorobiphenyl (PCB118)-induced thyroid dysfunction, Fischer rat thyroid cell line-5(FRTL-5) cells were treated with either different concentrations of PCB118 or dimethyl sulfoxide (DMSO). The(More)
To investigate the prevalence of thyroid nodules (TN) among a community population aged >40 years and to explore the association between TN and its metabolic risk factors. Data from 9,533 adults aged over 40 years who participated in the epidemiological investigation of thyroid nodules in a Chinese community-based population from June to December 2011 were(More)
Polychlorinated biphenyls (PCBs) are typical persistent organic pollutants that can interfere with multiple organ systems of humans. Previously, we concluded that persistent exposure to low doses of PCB118 could severely damage the thyroidal structure, dramatically decrease the concentration of serum thyroid hormones and inhibit the pivotal gene expressions(More)
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