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OBJECTIVE Currently, research is focused on universal influenza vaccines based on various ectodomains of the influenza matrix protein 2 (M2e). Such vaccines are tested mostly using mouse-adapted influenza viruses and in mouse or ferret models. The aim of this study was to investigate in a chicken model the protective efficacy of vaccines based on avian-type(More)
A hybrid genetic algorithm is proposed for multi-objective flexible job-shop scheduling problem, where the time, cost and equipment utilization rate are used as objective functions. First, the scheduling model for this problem is set up. Second, the matrix chromosome based on job-scheduling encode is adopted and it makes the decode and the use of belief(More)
To investigate the effects of personality type and psychological stress on the occurrence of major adverse cardiovascular events (MACEs) at 5 years in patients with coronary artery disease (CAD) after percutaneous coronary intervention (PCI). Two hundred twenty patients with stable angina (SA) or non-ST segment elevation acute coronary syndrome (NSTE-ACS)(More)
Bus trip is a healthy way to travel, and optimal bus dispatching decides social and economic benefits. Based on the analysis for both the existing traffic environment and bus dispatching, a mathematical model is proposed in this paper such that the goal function of this model are the average maximal satisfaction for passengers, the average loading rate of(More)
According to the characteristics of constrained optimization problem, a new approach based on a new fitness function is presented to handle constrained optimization problems. The primary features of the algorithm proposed are as follows. Inspired by the smooth function technique, a new fitness function is designed which can automatically search potential(More)
Bus trip is a healthy way to travel, and optimal bus dispatching decides social and economic benefits. Based on the analysis for both the existing traffic environment and bus dispatching, a mathematical model of the regional multi-line bus dispatching within is proposed in this paper such that the goal function of this model are the average maximal(More)