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We introduce a new iterative regularization procedure for inverse problems based on the use of Bregman distances, with particular focus on problems arising in image processing. We are motivated by the problem of restoring noisy and blurry images via variational methods, by using total variation regularization. We obtain rigorous convergence results, and(More)
In this paper we generalize the iterated refinement method, introduced by the authors in a recent work, to a time-continuous inverse scale-space formulation. The iterated refinement procedure yields a sequence of convex variational problems, evolving toward the noisy image. The inverse scale space method arises as a limit for a penalization parameter(More)
In this paper we generalize the iterated refinement method, introduced by the authors in [8], to a time-continuous inverse scale-space formulation. The iterated refinement procedure yields a sequence of convex variational problems, evolving toward the noisy image. The inverse scale space method arises as a limit for a penalization parameter tending to zero,(More)
In this paper, we generalize the iterative regularization method and the inverse scale space method, recently developed for total-variation (TV) based image restoration, to wavelet-based image restoration. This continues our earlier joint work with others where we applied these techniques to variational-based image restoration, obtaining significant(More)
Apoptosis is an important aspect of a number of biological processes, from embryogenesis to the stress-injury response. It plays a central role in balancing cell proliferation and tissue remodeling activity in many organisms. In the present study, apoptosis in 14 days post infection schistosomula was evaluated using TUNEL (terminal deoxynucleotidyl(More)
We introduce a new iterative regularization procedure for inverse problems based on the use of Bregman distances, with particular focus on problems arising in image processing. We are motivated by the problem of restoring noisy and blurry images via variational methods, specifically by using the BV seminorm. Although our procedure applies in quite general(More)
Histomonas meleagridis is the causative agent of histomonosis, a disease of gallinaceous fowl characterized by necrotic typhlitis, hepatitis, and high mortality. To develop a rapid and sensitive method for specific detection of H. meleagridis, an assay based on loop-mediated isothermal amplification (LAMP) targeting the 18S rRNA gene was established. The(More)
Cyclophilins belong to a group of proteins that have peptidyl-prolyl cis-trans isomerase activity and have been identified in all cell types and all organisms studied. In both prokaryotes and eukaryotes, they have been characterized as functional chaperones and involved in cell signaling. In the present study, Sj cyclophilin A (CyPA) was cloned,(More)
Schistosomiasis remains an important global public health problem that affects 200 million people in 76 countries. The molecular mechanisms of host-parasite interaction are complex, and in schistosome infection regulation of microRNA (miRNA) and the host micro-environment may be involved. In this study, an miRNA microarray was applied to investigate(More)