Jinhong Guo

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Circulating tumor cells (CTCs), which are derived from primary tumor site and transported to distant organs, are considered as the major cause of metastasis. So far, various techniques have been applied for CTC isolation and enumeration. However, there exists great demand to improve the sensitivity of CTC capture, and it remains challenging to elute the(More)
Lensless microfluidic imaging with super-resolution processing has become a promising solution to miniaturize the conventional flow cytometer for point-of-care applications. The previous multi-frame super-resolution processing system can improve resolution but has limited cell flow rate and hence low throughput when capturing multiple subpixel-shifted cell(More)
In this study, we present a simple technique capable of assembling and patterning suspended CNTs using a standing surface acoustic wave (SSAW) field. Individual CNTs could be assembled into larger CNT bundles and patterned in periodic positions on a substrate surface. The mechanism of the SSAW-based patterning technique has been investigated using both(More)
Acoustophoresis-based particle manipulation in microfluidics has gained increasing attention in recent years. Despite the fact that experimental studies have been extensively performed to demonstrate this technique for various microfluidic applications, numerical simulation of acoustophoresis driven by surface acoustic waves (SAWs) has still been largely(More)
Surface Acoustic Wave (SAW) has emerged as a powerful technique for kinds of application, such as gas sensor, on-chip manipulation of microparticles or biological cells. In this paper, we present a numerical simulation and experimental study of standing surface acoustic wave (SSAW) induced acoustophoresis to assemble the particle samples in a microchannel.(More)
Conventional Coulter counters have been introduced as an important tool in biological cell assays since several decades ago. Recently, the emerging portable Coulter counter has demonstrated its merits in point of care diagnostics, such as on chip detection and enumeration of circulating tumor cells (CTC). The working principle is based on the cell(More)
The extraordinary properties of layered graphene and its successful applications in electronics, sensors, and energy devices have inspired and renewed interest in other two-dimensional (2D) layered materials. Particularly, a semiconducting analogue of graphene, molybdenum disulfide (MoS2), has attracted huge attention in the last few years. With efforts in(More)
Portable devices have been introduced to provide companion diagnostics in many applications such as personalized healthcare monitoring since several decades ago. Recently the polydimethylsiloxane (PDMS)-based microfluidic chip enables a cost effective platform for point of care diagnostics. In this paper, we present a systematic theoretical and experimental(More)
Coulter principal based resistive pulse sensor has been demonstrated as an important platform in biological cell detection and enumeration since several decades ago. Recently, the miniaturized micro-Coulter counter has attracted much attention due to its advantages in point of care diagnostics for on chip detection and enumeration of rare cells, such as(More)
We report the world's first medical smartphone as an electrochemical analyzer, which is incorporated with an enzymatic test strip for rapid characterization of UA (uric acid) in peripheral whole blood. A disposable electrochemical uric acid test strip was connected to the electrochemical module integrated with the smartphone through a specific interface, a(More)