Donald A. McClain2
Judith A. Simcox2
Khadega A. Abuelgasim1
Adelina Sergueeva1
2Donald A. McClain
2Judith A. Simcox
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In Chuvash polycythemia, a homozygous 598C>T mutation in the von Hippel–Lindau gene (VHL) leads to an R200W substitution in VHL protein, impaired degradation of α-subunits of hypoxia-inducible factor (HIF)-1 and HIF-2, and augmented hypoxic responses during normoxia. Chronic hypoxia of high altitude is associated with decreased serum glucose and insulin(More)
A 15N dilution experiment was carried out to investigate effects of cultivation on the gross N transformation rate in coastal wetland zone. Microbial community composition was estimated by phospholipid fatty acid (PLFA) analysis and abundance of soil ammonia-oxidizing bacteria (AOB) was quantified by real-time polymerase chain reaction (PCR). Soil salinity(More)
The circadian rhythm of the liver maintains glucose homeostasis, and disruption of this rhythm is associated with type 2 diabetes. Feeding is one factor that sets the circadian clock in peripheral tissues, but relatively little is known about the role of specific dietary components in that regard. We assessed the effects of dietary iron on circadian(More)
Characterizing the empirical distribution of the frequency of n-mers is a vital step in understanding the entire genome. This will allow for researchers to examine how complex the genome really is, and move beyond simple, traditional modeling frameworks that are often biased in the presence of abundant and/or extremely rare words. We hypothesize that models(More)
The production of L-leucine from pure botanical sources is expensive and time consuming. Hence, most fraudulent manufacturers in China use cheap and sometimes unwholesome sources of raw materials such as human hair and duck feathers in its production. Consequently, major concerns on health, economic, religious, legal and allergic reaction cases have been(More)
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