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Genome-wide association studies (GWAS) have linked genetic variants at 9p21.3 to the risk of multiple cancers. However, the roles of genetic variants at 9p21.3 in esophageal squamous cell carcinoma (ESCC) development are largely unknown. Here we evaluated the genetic variants at 9p21.3 reported in cancer GWAS with case-control study including 2,139 ESCC(More)
OBJECTIVE To assess the feasibility and result of endovascular treatments for ruptured peripheral intracranial aneurysms. METHODS We retrospectively reviewed our experience and results of endovascular treatments for a series of 18 consecutive patients with ruptured distal intracranial aneurysms at the Department of Neurosurgery, Southwest Hospital,(More)
Resource allocation mechanism plays a critical role towards the success of cloud computing. Existing allocation mechanisms in public cloud is unsuitable to private IaaS cloud because they either cannot maximize the sum of users value, or provide no service guarantee. For overcome these shortcomings, we propose a novel online, model-free mechanism that makes(More)
BACKGROUND HOX transcript antisense intergenic RNA (HOTAIR), a long non-coding RNA transcribed from the antisense strand of the HOXC gene locus, has been shown to be overexpressed in various carcinomas and is thought to be an indicator of poor prognosis. Recently, HOTAIR was found to be an estrogen-responsive gene. We therefore conducted a meta-analysis to(More)
Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) and the proliferating antigen Ki67 have been widely studied in several tumors. However, their role as indicator in non-small cell lung cancer (NSCLC) remains unknown. Here, we investigated the expression of PTEN and Ki67 in NSCLC tissues and paired normal lung tissues to identify whether these(More)
Excessive oxidative stress poses significant damage to yeast cells during fermentation process, and finally affects fermentation efficiency and the quality of products. In this paper, global transcription machinery engineering was employed to elicit Saccharomyces cerevisiae phenotypes of higher tolerance against oxidative stress caused by H2O2. Two strains(More)
—Due to the inaccuracy and noisy, uncertainty is inherent in time series streams, and increases the complexity of streams clustering. For the continuous arriving and massive data size, efficient data storage is a crucial task for clustering uncertain data streams. With hash-compressed structure, an extended uncertain sketch and update strategy are proposed(More)
—Uncertainty is inherent in data streams, and present new challenges to data streams mining. For continuous arriving and large size of data streams, modeling sequences of uncertain time series data streams require significantly more space. Therefore, it is important to construct compressed representation for storing uncertain time series data. Based on(More)
Hemorrhagic events associated with cerebral paragonimiasis are not rare, especially in children and adolescents; however, angiographic evidence of cerebrovascular involvement has not been reported. The authors describe angiographic abnormalities of the cerebral arteries seen in 2 children in whom cerebral paragonimiasis was associated with hemorrhagic(More)