Jingyao Dai

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Extracellular matrix metalloproteinase inducer (EMMPRIN) plays a critical role in the progression of malignancies by stimulating expression of metalloproteinases (MMPs) and vascular endothelial growth factor (VEGF) in stromal cells. However, the expression of EMMPRIN in adenoid cystic carcinoma (ACC) of salivary glands, and its correlation with patients'(More)
The regulator of G-protein signaling (RGS) pathway plays an important role in signaling transduction, cellular activities, and carcinogenesis. We hypothesized that genetic variations in RGS gene family may be associated with the response of late-stage non-small cell lung cancer (NSCLC) patients to chemotherapy or chemoradiotherapy. We selected 95 tagging(More)
Recent genome-wide association studies (GWAS) have identified several common susceptibility loci associated with the risk of colorectal cancer (CRC). However, whether these loci affect clinical outcomes of CRC is not clear. In this study, we genotyped 26 single nucleotide polymorphisms (SNPs) in 10 GWAS-identified CRC susceptibility regions and evaluated(More)
Energy efficiency has proven to be an important factor dominating the working period of WSN surveillance systems. Intensive studies have been done to provide energy efficient power management mechanisms. In this paper, we present PAS, a Prediction-based Adaptive Sleeping mechanism for environment monitoring sensor networks to conserve energy. PAS focuses on(More)
Base excision repair (BER) is one of the major cellular DNA repair pathways that repairs small isolated foci of DNA damage including reduced or oxidized single bases or fragments and small, non-bulky adducts. Genetic variations in BER genes may affect DNA repair capacity and increase susceptibility to bladder cancer. In a case-control study of 801 bladder(More)
BACKGROUND The VEGF-independent angiogenic signaling plays an important role in the development of colorectal cancer (CRC). However, its implication in the clinical outcome of CRC has not been reported. This study aimed to investigate the association between genetic variations in several major VEGF-independent signaling pathway genes and the overall(More)
This paper presents the design of a Kindred-based QoS-aware Live Media Streaming (KQStream) system in heterogeneous peer-to-peer environments. Motivated by the Multiple Description Coding technique, we propose a novel kindred-based approach to construct a peer-to-peer overlay topology. To achieve QoS-awareness during the streaming process, we propose a(More)
BACKGROUND Previous studies have demonstrated that ATP citrate lyase (ACLY) plays an important role in the development of many cancers. Our current study aims to assess the effects of functional single nucleotide polymorphisms (SNPs) in ACLY gene on recurrence and survival of colorectal cancer (CRC) patients. METHODS A total of 697 resected Chinese CRC(More)
China accounts for 19% of the world population1 but only 5.5% of total gross domestic product for health expenditures.2Most of themedical resources (eg,welltrained medical workers, advanced medical equipment) are concentrated in large tertiary hospitals. The large tertiaryhospitals in the largecitieshavebeenovercrowded and adversely affected by the(More)