Learn More
Both sequence-based and activity-based exploitation of environmental DNA have provided unprecedented access to the genomic content of cultivated and uncultivated microorganisms. Although researchers deposit microbial strains in culture collections and DNA sequences in databases, activity-based metagenomic studies typically only publish sequences from the(More)
Soil microbial diversity represents the largest global reservoir of novel microorganisms and enzymes. In this study, we coupled functional metagenomics and DNA stable-isotope probing (DNA-SIP) using multiple plant-derived carbon substrates and diverse soils to characterize active soil bacterial communities and their glycoside hydrolase genes, which have(More)
Fluorescence molecular tomography (FMT) is a fast-developing optical imaging modality that has great potential in early diagnosis of disease and drugs development. However, reconstruction algorithms have to address a highly ill-posed problem to ful¯ll 3D reconstruction in FMT. In this contribution, we propose an e±cient iterative algorithm to solve the(More)
  • 1