Jinguang Wang

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By inspiring the motion of magnetotactic bacterium, a bionic micro-machine swimming in the liquid was proposed in the paper. The bionic micro-machine is propelled by the propeller fixed onto the motor shaft, and the motor's start-up, stop and speed are controlled by wireless radio transceiver modules. The moving attitude of the bionic micro-machine is(More)
The G-quadruplex DNA formed by the stack of guanines in human telomere sequence is a promising anticancer target. In this study we used the energy landscape theory to elucidate the folding mechanisms for the thrombin aptamer, Form 1 and Form 3 G-quadruplexes. The three G-quadruplexes were simulated with all-atom Gō-model. Results show that, the three(More)
The most important requirement of biomolecular modeling is to deal with electrostatic energies. The electrostatic polarizability is an important part of electrostatic interaction for simulation systems. However, AMBER, CHARMM, OPLS, GROMOS, MMFF force fields etc. used in the past mostly apply fixed atomic center point charge to describe electrostatic(More)
Optical recording with fast voltage sensitive dyes makes it possible, in suitable preparations, to simultaneously monitor the action potentials of large numbers of individual neurons. Here we describe methods for doing this, including considerations of different dyes and imaging systems, methods for correlating the optical signals with their source neurons,(More)
Different quantum mechanic methods have been evaluated for the calculation of binding modes and interactions between intercalators with different DNA base pairs by comparing with the results of MP2, which is very expensive, indicating that WB97XD method under 6-311+G* basis set is able to efficiently reproduce MP2 results. We discovered that the methylene(More)
Sky luminance model recognition algorithm is proposed, using particle swarm optimization. Based on spatial distribution of daylight CIE standard general sky, intelligent particle swarm optimization algorithm is applied to compute and recognize arbitrary sky. Hence the type of current sky can be identified quickly. The algorithm lays a theory foundation for(More)
Most proteins need to avoid the complex topologies when folding into the native structures, but some proteins with nontrivial topologies have been found in nature. Here we used protein unfolding simulations under high temperature and all-atom Gō-model to investigate the folding mechanisms for two trefoil knot proteins. Results show that, the contacts in(More)
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