Jingrui Zhang

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Isoniazid (INH) and rifampicin (RIF) are the two most effective drugs in tuberculosis therapy. Understanding the molecular mechanisms of resistance to these two drugs is essential to quickly diagnose multidrug-resistant (MDR) tuberculosis and extensive drug-resistant tuberculosis. Nine clinical Mycobacterium tuberculosis isolates resistant to only INH and(More)
In this study, 24 standard nontuberculous mycobacteria (NTM) species strains including 12 slowly growing mycobacteria strains and 12 rapidly growing mycobacteria strains were subjected to drug susceptibility testing using microplate Alamar Blue assay-based 7H9 broth. The most active antimicrobial agents against the 24 NTM strains were streptomycin,(More)
Iron is essential for organisms. It is mainly utilized in mitochondria for biosynthesis of iron-sulfur clusters, hemes and other cofactors. Mitoferrin 1 and mitoferrin 2, two homologues proteins belonging to the mitochondrial solute carrier family, are required for iron delivery into mitochondria. Mitoferrin 1 is highly expressed in developing erythrocytes(More)
—To understand users' preference and business performance in terms of customer interest, rating prediction systems are wildly deployed on many social websites. These systems are usually based on the users past history of reviews and similar users. Such traditional recommendation systems 1 suffer from two problems. The first is the cold start problem. In(More)
Physics-Based Simulations for Fluid Mixtures 2007 We develop a physics-based particle method to simulate various fluid mixture effects. A particle method is chosen over a grid-based method because we believe a particle method is more intuitive and better suited for handling physical and chemical interactions between fluids. Since a particle carries the(More)
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