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Prediction of protein subcellular location is a meaningful task which attracted much attention in recent years. A lot of protein subcellular location predictors which can only deal with the single-location proteins were developed. However, some proteins may belong to two or even more subcellular locations. It is important to develop predictors which will be(More)
A new spike sorting method based on the support vector machine (SVM) is proposed to resolve the superposition problem. The spike superposition is generally resolved by the template matching. Previous template matching methods separate the spikes through linear classifiers. The classification performance is severely influenced by the background noise(More)
The characteristics of the antibiotic fermentation process with parallel lines are analyzed. The assignment of tasks, units and events is described by two sets of binary variables. Based on continuous time representation, a mixed integer linear programming (MILP) model of the antibiotic fermentation process is built. The computational example of(More)
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