Jingmin Zhou

Learn More
Signature-based network intrusion-detection systems (NIDSs) often report a massive number of simple alerts of low-level security-related events. Many of these alerts are logically involved in a single multi-stage intrusion incident and a security officer often wants to analyze the complete incident instead of each individual simple alert. This paper(More)
BACKGROUND Endostar™ (rh-endostatin, YH-16) is a new recombinant human endostatin developed by Medgenn Bioengineering Co. Ltd., Yantai, Shandong, P.R.China. Pre-clinical study indicated that YH-16 could inhibit tumor endothelial cell proliferation, angiogenesis and tumor growth. Phase I and phase II studies revealed that YH-16 was effective as single agent(More)
We propose a method to verify the result of attacks detected by signature-based network intrusion detection systems using lightweight protocol analysis. The observation is that network protocols often have short meaningful status codes saved at the beginning of server responses upon client requests. A successful intrusion that alters the behavior of a(More)
Adeno-associated virus (AAV) empty capsids typically co-purify with genome containing AAV2 vectors purified by column chromatography. This study describes a method to remove empty capsids from genome containing vector particles by anion exchange chromatography. The separation is based on the slightly less anionic character of empty particles compared to(More)
Incomplete or improper input validation is one of the major sources of security bugs in programs. While traditional approaches often focus on detecting string related buffer overflow vulnerabilities, we present an approach to automatically detect potential integer misuse, such as integer overflows in C programs. Our tool is based on CQual, a static analysis(More)
Coronary tortuosity (CT) would alter the local wall shear stress (WSS) and may become a risk factor for atherosclerosis. Here we performed a systematic computational study to relate CT morphological parameters to abnormal WSS, which is a predisposing factor to the formation of atherosclerotic lesions. Several idealized left coronary artery (LCA) models were(More)
Column chromatography has been described for purification of recombinant adeno-associated viral vectors (rAAV) serotypes 1, 2, 5, 6 and 8. Some of these purification processes have been used in manufacturing pre-clinical grade and clinical grade rAAV vectors. Recently, recombinant AAV9 has been reported to be highly efficient in transducing cardiac muscle(More)
BACKGROUND The effect of ACE inhibitors on the prognosis of chronic heart failure patients with preserved left ventricular ejection fraction remains controversial. AIMS To assess the impact of ACE inhibitors on the prognosis of chronic heart failure patients with preserved left ventricular ejection fraction. METHODS AND RESULTS Seven prospective studies(More)