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The objective of this study was to analyze the expression of cathepsin B (CTSB) and its clinicopathological significance in patients with hepatocellular carcinoma (HCC). The expression of CTSB mRNA was analyzed in Oncomine database. The expression of CTSB protein in 90 specimens of HCC and paired non-tumor tissue microarray (TMA) was determined by(More)
T cell immunodeficiency is a common feature in cancer patients and may be a contributing factor to the initiation and development of the tumor. In order to characterize the immune status in a group of patients with diffuse large B-cell lymphoma (DLBL), the repertoires of T cell receptor alpha and beta variable regions (TRAV and TRBV) were analyzed. The CDR3(More)
OBJECTIVE The objective of this study was to analyze the expression of TARBP1 and its clinical significance in hepatocellular carcinoma (HCC). MATERIALS AND METHODS 90 patients with primary hepatocellular carcinoma were included in this study. The tumor and paired adjacent non-tumor tissues were collected. TARBP1 expression was assessed by quantitative(More)
T-cell immunodeficiency is a common feature in cancer patients, but clonally expanded T cells which were considered to have the specific anti-tumor cytotoxicity can be identified in most cancer patients, including those with hematological malignancies. We previously reported that there were skewed usages of T-cell receptor (TCR) Valpha and TCR Vbeta(More)
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