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In addition to their protein coding function, exons can also serve as transcriptional enhancers. Mutations in these exonic-enhancers (eExons) could alter both protein function and transcription. However, the functional consequence of eExon mutations is not well known. Here, using massively parallel reporter assays, we dissect the enhancer activity of three(More)
What is the best account to explain the object-based attentional benefit-that is, the spread of attention within an attended object or prioritization of search across possible target locations within an attended object? Using a task in which the location of the target was known with certainty, in the present study we systematically manipulated the type(More)
How do human listeners differentiate one language from another? In this study we examine the contributions of acoustic and linguistic cues to successful language discrimination. In particular, we report findings that reveal patterns of cortical competition as a function of the competition between prosodic, phonological, and lexical semantic information(More)
Thermophiles are referred to as microorganisms with optimal growth temperatures of >60 °C. Over the past few years, a number of studies have been conducted regarding thermophiles, especially using the omics strategies. This review provides a systematic view of the survival physiology of thermophiles from an "omics" perspective, which suggests that the(More)
Using photocatalytic reactive nanoparticles and DNA composite modified gold electrodes, exploiting the sensitivity of DNA-mediated electron transfer to base pair stacking, we examined the effects of DNA oxidation damage by photocatalytically generated hydroxyl radicals (˙OH) on charge transfer efficiency and proposed an electrochemical technique to read the(More)
This paper focuses on the problem of scene classification for mobile robots in an outdoor environment. We present a novel model that combines biologically inspired features and cortex-like memory patterns. The biologically inspired gist feature is used to characterize the content of a scene image. The Incremental Hierarchical Discriminant Regression tree is(More)
Bisphenol A (BPA) is a widespread endocrine-disrupting chemical used as the building block for polycarbonate plastics. Epidemiological evidence has correlated BPA exposure with higher risk of heart disease and type 2 diabetes. However, it remains unknown whether there are critical windows of susceptibility to BPA exposure on the development of dysglycemia.(More)
The aim of the present study was to test the model of relationships between dispositional mindfulness, core self-evaluations and life satisfaction in a sample of Chinese adults. Three hundred and ten participants with an age range of 18–50 years completed the Mindful Attention Awareness Scale (MAAS), the Core Self-evaluations Scale (CSES) and the(More)
The paper focuses on the modeling of visual saliency. We present a novel model to simulate the two stages of visual processing that are involved in attention. Firstly, the proto-object features are extracted in the pre-attentive stage. On the one hand, the salient pixels and regions are extracted. On the other hand, the semantic proto-objects, which involve(More)