Jingjing Yang

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Persistent hepatitis C virus (HCV) infection can lead to chronic inflammation and even carcinogenesis. This may in part be due to various viral proteins, which affect apoptosis and promote liver cell growth. Recently, researchers reported a novel F protein, an alternative reading frame protein expressed from the HCV core coding sequence. The functional(More)
Severe acute respiratory syndrome (SARS) coronavirus has been known to damage multiple organs; however, little is known about its impact on the reproductive system. In the present study, we analyzed the pathological changes of testes from six patients who died of SARS. Results suggested that SARS caused orchitis. All SARS testes displayed widespread germ(More)
This study was performed to investigate the angiotensin I-converting enzyme (ACE) inhibitory activity of peptides derived from fertilized eggs and elucidate the inhibition mechanism of these peptides. During incubation, ACE inhibitory activity of the peptides remained stable before day 12 and then increased markedly on day 15. Two ACE inhibitory peptides,(More)
Expression of MDM2 protein appears to be increased in malignancy and correlated to prognosis of tumors, but its role in gastric cancer remains controversial. Our recent investigations indicated that JWA was a novel candidate biomarker for gastric cancer. To evaluate the impact of MDM2 protein expression alone, and in combination with JWA, on the prognostic(More)
BACKGROUND We aimed to evaluate the function of coronary collateral circulation (CCC) in the ischemic myocardium by a two-dimensional strain technique. METHODS AND RESULTS Myocardial segments for all patients were divided into three groups: no coronary collateral circulation (NCCC), CCC, and normal control. We obtained the segmental strain and the strain(More)
Thiazide diuretics are widely used for the management of hypertension. In recent years, it has been actively debated that there is interchangeability of thiazide-type diuretics hydrochlorothiazide and thiazide-like diuretics including indapamide and chlorthalidone for the treatment of hypertension. With the purpose of seeking out the best thiazide diuretic(More)
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