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Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson's disease.
Human pluripotent stem cells (PSCs) are a promising source of cells for applications in regenerative medicine. Directed differentiation of PSCs into specialized cells such as spinal motoneurons orExpand
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Human embryonic stem cell-derived oligodendrocyte progenitors remyelinate the brain and rescue behavioral deficits following radiation.
Radiation therapy to the brain is a powerful tool in the management of many cancers, but it is associated with significant and irreversible long-term side effects, including cognitive decline andExpand
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Neuroprotective effects of human spinal cord-derived neural precursor cells after transplantation to the injured spinal cord
To validate human neural precursor cells (NPCs) as potential donor cells for transplantation therapy after spinal cord injury (SCI), we investigated the effect of NPCs, transplanted as neurospheres,Expand
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Specification of functional cranial placode derivatives from human pluripotent stem cells.
Cranial placodes are embryonic structures essential for sensory and endocrine organ development. Human placode development has remained largely inaccessible despite the serious medical conditionsExpand
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Derivation of Diverse Hormone-Releasing Pituitary Cells from Human Pluripotent Stem Cells
Summary Human pluripotent stem cells (hPSCs) provide an unlimited cell source for regenerative medicine. Hormone-producing cells are particularly suitable for cell therapy, and hypopituitarism, aExpand
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Floor plate-derived dopamine neurons from hESCs efficiently engraft in animal models of PD
Human pluripotent stem cells (PSCs) are a promising source of cells for applications in regenerative medicine. Directed differentiation of PSCs into specialized cells such as spinal motoneurons orExpand
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"I Think You'll Like It"
Understanding the roles of social factors in online purchase behavior has been a long standing research problem. The recently emerging social e-commerce platforms leverage the stimulatedExpand
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Long-term clinically relevant rodent model of methotrexate-induced cognitive impairment.
BACKGROUND With the enhanced use of chemotherapy and the advent of increased patient survival rates, there is an increasing number of cancer survivors living with chemotherapy-induced cognitiveExpand
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STEM-17REPAIR OF RADIATION INJURY TO THE BRAIN USING HUMAN PLURIPOTENT STEM CELL DERIVED OLIGODENDROCYTE PROGENITORS
Radiation therapy (RT) to the brain remains a powerful tool in the management of a wide range of cancers of the brain, head and neck regions and brain metastases. It is also used in prophylaxis inExpand