Jinggang Xia

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OBJECTIVES We explored whether preoperative rosuvastatin could protect the cardiac health of patients with coronary artery disease undergoing emergency, noncardiac surgery. METHODS We randomized 550 noncardiac emergency surgery patients with stable coronary artery disease on long-term statin therapy to treatment with and without preoperative rosuvastatin.(More)
OBJECTIVE This study was designed to investigate whether patients with stable coronary artery disease (CAD) receiving chronic statin treatment who are undergoing noncardiac emergency surgery benefit from acute atorvastatin reload. METHODS A total of 500 patients with stable CAD and regular administration of statin before noncardiac emergency surgery were(More)
The aim of the present study was to investigate the effects of glucose fluctuation on neointimal proliferation after stent implantation by optical coherence tomography (OCT) in a diabetic/hypercholesterolemic (DM/HC) swine model.A total of 24 everolimus-eluting stents (EES) were implanted in the right coronary artery (RCA) of the animals using a 20%(More)
(I21⁄40%, p1⁄40.66). Overall, IVUS-guidance was associated with significant reduction in MACE (Figure). In total, 5,108 and 3,157 patients received firstand second-generation DES, respectively. IVUSguidance was associated with significant reduction in MACE in both first(OR 0.79, 95%CI 0.67-0.92, p1⁄40.03) and second-generation DES (OR 0.56, 95%CI 0.41-0.77,(More)
BACKGROUND We explored the impact of glycemic variability on the occurrence of periprocedural myocardial infarction and major adverse cardiovascular events (MACE) after coronary intervention in patients with stable angina pectoris (SAP) at 6months follow-up. METHODS From May 2015 to April 2016, a total of 746 patients with SAP were divided to high(More)
BACKGROUND We explored the association between glycemic variability and major adverse cardiovascular and cerebrovascular events (MACCE) in patients with acute coronary syndrome (ACS) during 30-day follow-up. METHODS From May 2013 to April 2015, a total of 864 patients with ACS were divided to high glycemic variability group (H group) (n=285) and low(More)
BACKGROUND Statins have proven cardioprotective effects, but higher doses are accompanied by various concerns and may not lead to superior clinical outcomes in Chinese/Asian populations. OBJECTIVE We designed a trial to test the efficacy of high-intensity statin therapy for the reduction of periprocedural myocardial infarction (MI) and 1-year major(More)
BACKGROUND This study aimed to evaluate the role of b-blocker therapy on modulating interleukin (IL)-33/ST2 (interleukin-1 receptor-like 1) signaling during ventricular remodeling related to heart failure (HF) after acute myocardial infarction (AMI). METHODS Sprague-Dawley rats that survived surgery to induce AMI were randomly divided into the placebo(More)
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