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X-ray repair cross complementing group 1 (XRCC1) is one of the major DNA repair proteins involved in the base-excision repair pathway. Functional Polymorphisms in the XRCC1 gene may lead to decreased DNA repair capacity and thus confer inherited predisposition to cancer risk. In this case-control study of 710 patients with incident lung cancer and 710(More)
PURPOSE Matrix metalloproteinase 9 (MMP-9) plays critical roles in cancer development and aggression. Nonsynonymous single-nucleotide polymorphisms (SNP) in the functional domain of the MMP-9 gene may influence substrate and inhibitor binding and contribute to cancer predisposition and aggression. PATIENTS AND METHODS To test our hypothesis that common(More)
In this paper, we introduce an image segmentation method based on multiresolution and scale-space theory. Specifically, a nonlinear scale-space stack is constructed by anisotropic wavelet shrinkage. A tree structure is derived from the stack based on the relationships between connected components of adjacent scale layers. Then, Equivalent framework of(More)
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