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Visfatin is an adipocytokine that plays an important role in attenuating insulin resistance by binding to insulin receptor. It has been suggested that visfatin plays a role in the regulation of cell apoptosis and inflammation by an as yet unidentified mechanism. This study investigated the protective effects of visfatin on palmitate-induced islet β-cell(More)
OBJECTIVES This study was designed to test the hypothesis that normal thyroid function is associated with non-alcoholic fatty liver disease (NAFLD) in euthyroid general subjects. METHODS A total of 739 euthyroid subjects were enrolled in this cross-sectional study. Using ultrasound, a diagnosis of NAFLD was made in subjects without a history of excessive(More)
T2D is a metabolic and inflammatory disease characterized by deteriorating β-cell function and increased levels of inflammatory cytokines. Low-grade inflammation and innate immune system activation lead to β-cell failure. Recently, SFAs have been proposed as triggers of metabolism-associated inflammation through the TLR family of PRRs. In this review,(More)
The objective of this study is to present a familial Cushing syndrome (CS) caused by multiple endocrine neoplasia type 1 (MEN-1)-associated thymic carcinoid. Immunohistochemistry, gene sequencing, loss of heterozygosity analysis, and Western blot were used to determine the expression of ACTH in MEN-1-related thymic tumors, MEN1 gene mutation, the pattern(More)
Objective. To investigate the association of thyroid function and diabetic nephropathy (DN) in euthyroid patients with type 2 diabetes. Methods. A total of 421 patients were included in this cross-sectional study. The following parameters were assessed: anthropometric measurements, fast plasma glucose, serum creatinine, lipid profile, HbA1c, free(More)
BACKGROUND Even within the reference range, thyrotropin (TSH) levels were found to be positively associated with the risk of cardiovascular disease (CVD). However, the underlying mechanism of TSH remains ambiguous. This study investigated the association of TSH with cardiovascular risk factors among healthy Chinese subjects and subjects with unsuspected(More)
Restriction site-associated DNA sequencing (RAD-seq) was used to illuminate the genetic relationships among Eriobotrya species. The raw data were filtered, and 221 million clean reads were used for further analysis. A total of 1,983,332 SNPs were obtained from 23 Eriobotrya species and two relative genera. We obtained similar results by neighbor-joining and(More)
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