Jingchen Zheng

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AIMS 17α-hydroxylase/17,20-lyase deficiency (17OHD) is characterized by impaired productions of gonadal steroids and cortisol, a subsequent elevation of adrenocorticotropic hormone, and accumulation of steroid precusors, which are shunted into the mineralocorticoid synthesis pathway. This disease is caused by mutations in the CYP17 gene. In this paper, we(More)
To address whether mutations and single nucleotide polymorphisms (SNPs) in perforin gene (PRF1) are correlated with acute lymphoblastic leukemia (ALL) in Chinese, we screened mutations in codon region of PRF1 in 111 ALL patients, and correlated the results with patients' immunophenotype, karyotype and fusion genes. Four novel monoallelic missense and two(More)
MapReduce is an important distributed programming model for large-scale data-parallel applications like web indexing, data mining, and scientific simulation. Hadoop is an open-source implementation of MapReduce and it is often applied to short jobs for which low response time is critical. When the cluster nodes are homogeneous, Hadoop has a good(More)
BACKGROUND The use of serum anti-hepatitis B core antibody (HBc)-positive/hepatitis B surface antigen (HBsAg)-negative liver donors for patients with hepatitis B virus (HBV)-related liver disease (HBRLD) is a promising means of expanding the organ donor pool and does not increase the risk of HBV recurrence. However, whether such donors will compromise the(More)
Dear editor, A 49-year-old woman was presented with sudden headache, nausea, and vomiting. Head computed tomography (Figure 1(a)) and initial angiography taken in local hospital revealed subarachnoidhemorrhagewithout presentation of aneurysm. Review of 3D angiography (Figure 1(b)) 50 days later found a tiny aneurysm of basilar perforating artery.(More)
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