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We report the production of recombinant human lactoferrin in Aspergillus oryzae. Expression of human lactoferrin (hLF), a 78 kD glycoprotein, was achieved by placing the cDNA under the control of the A. oryzae α–amylase promoter and the 3′ flanking region of the A. niger glucoamylase gene. Using this system, hLF is expressed and secreted into the growth(More)
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