Jing-Wei Wang

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OBJECTIVE To investigate the effect of synthesized Her-2/neu specific siRNA on the cell cycle and apoptosis of Her-2/neu upregulating human lung adenocarcinoma cells. METHODS Human lung cancer cells of the line calu-3 were cultured and divided into 4 groups: untreated control group, blank vector group transfected with blank vector, non-specific siRNA(More)
BACKGROUND & OBJECTIVE C-erbB-2 gene is amplified or overexpressed in breast cancer, ovarian cancer, and lung cancer, and is related with enhanced malignancy and metastatic ability, intrinsic chemoresistance, and poor prognosis of tumors. RNA interfering (RNAi), a new genetic technique, can efficiently and specifically suppress gene expression. This study(More)
The aim of the present study was to investigate the expression levels of transforming growth factor-β (TGF-β) receptor type II (TβRII) and DPC4/Smad4 in the TGF-β signaling pathway and the importance of these expression levels in non-small cell lung cancer (NSCLC). The mRNA and protein expression levels of TβRII and DPC4/Smad4 were detected by reverse(More)
Service continuity is a critical issue in wireless networks. Unfortunately, jamming attacks seriously threatens the continuity of wireless networks. The open nature of wireless mediums makes it vulnerable to any wireless capable devices. There are only few researches address the issue of how the service providers should deploy its topology or allocate its(More)
OBJECTIVE To explore the effect of synthesized siRNA targeting Her2/neu oncogene on the drug sensitivity of Her2/neu-overexpressing lung adenocarcinoma cell line. METHODS The experiments consisted of four groups including an untreated control group, an empty vector group, an unrelated siRNA group, and a Her2/neu siRNA group. Every experiment was repeated(More)
OBJECTIVE To explore the role and potential mechanism of human α-defensin 1 (HNP-1) on low-density lipoprotein (LDL) oxidation ability of human endothelial cells (EVC304). METHODS Post incubation with LDL for 3 h, the malondialdehyde (MDA) and protein carbonyl (PCO) were detected in untreated ECV304 (control) and in HNP-1 transfected ECV304 in the(More)
Continuity of wireless networks is a critical issue for wireless networks. Unfortunately, there is a category of attacks that seriously threatens the continuity of wireless networks: the jamming attack. The open nature of wireless mediums makes them vulnerable to any wireless capable devices. However, there have not been any studies that address the issue(More)
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