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Autophagy is responsible for the degradation of long-lived proteins and damaged organelles intracellular, even extracellular,and autophagy is proved to have relationship with Alzheimer's disease (AD) and aging. The senescence accelerated mouse prone 8 (SAMP8) was a non-genetically modified mice widely used as a rodent model of aging and senile dementia.(More)
—Visual function in humans degrades during the early stage of senescence beginning from middle 50s to 60s. Generally,it may derive from the general decline of cortex inhibition,which destroys the balance between excitation and inhibition system in the brain.To date, the optimal fitting model of receptive field size curve is not clear during different age(More)
Chronic high-frequency repetitive transcranial magnetic stimulation (rTMS) is a noninvasive brain stimulation technique that has recently received increasing interests as a therapeutic procedure for neurodegenerative diseases. To identify the metabolism mechanism underlying the improving effects of rTMS, we observed that high frequency (25Hz) rTMS for 14(More)
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