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Interferon consensus sequence binding protein (ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Mice with a null mutation of ICSBP exhibit two prominent phenotypes related to previously described activities of the IRF family. The first is enhanced susceptibility to virus infections associated with impaired production(More)
Regarded as an emerging diarrheal micropathogen, Vibrio cholerae serogroup O139 was first identified in 1992 and has become an important cause of cholera epidemics over the last two decades. O139 strains have been continually isolated since O139 cholera appeared in China in 1993, from sporadic cases and dispersed foodborne outbreaks, which are the common(More)
A quasi-three-dimensional suspended sediment transport model was developed and generalized to include combined wave-current effects to study bottom sediment resuspension and transport in southern Lake Michigan. The results from a three-dimensional circulation model and a wind wave model were used as input to the sediment transport model. Two effects of(More)
In this paper, we will address the issue of detecting small target in a color image from the perspectives of both stability and saliency. First, we consider small target detection as a stable region extraction problem. Several stability criteria are applied to generate a stability map, which involves a set of locally stable regions derived from sequential(More)
OBJECTIVE The aim of this study was to determine differences in diameter of cochlear nerves (CN) among three measurement points at the midpoint of the internal auditory canal (IAC), IAC fundus and cochlear aperture, and to evaluate whether nerve size varies with age. METHODS A total of 336 normal-hearing ears of 201 children were assessed, who were(More)
Chaetomium globosum is one of the most common fungi in nature. It is best known for producing chaetoglobosins; however, the molecular basis of chaetoglobosin biosynthesis is poorly understood in this fungus. In this study, we utilized RNA interference (RNAi) to characterize a polyketide synthase gene, pks-1, in C. globosum that is involved in the production(More)
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