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Distinct pattern of Th17/Treg cells in pregnant women with a history of unexplained recurrent spontaneous abortion.
Investigation of the pattern of immune cells and related functional molecules in peripheral blood and at the maternal-fetal interface in women with unexplained recurrent spontaneous abortion found peripheral Treg cells did not increase in pregnant women with URSA.
A basic understanding of mucopolysaccharidosis: Incidence, clinical features, diagnosis, and management.
- Jing Zhou, Jing Lin, W. Leung, Ling Wang
- MedicineIntractable & rare diseases research
- 1 February 2020
Novel approaches including urinary and blood GAG test, enzyme assay and gene test help to diagnose MPS and to determine its subtype and new threatments, such as advanced ERT, gene therapy and substrate reduction therapy (SRT), improve therpeutic efficacy.
A general description for Chinese medicine in treating premature ovarian failure
A general description of CM treating POF from the aspects of mechanisms and clinical application is provided, including a range of common Chinese herbs and formulations according to the existing literature.
The immune dysfunction in ankylosing spondylitis patients.
Flow cytometry data suggested that patients with AS had an impairment in the ability to negatively regulate the immune response, which might be related to the etiology of AS.
Chromosomal karyotype in chorionic villi of recurrent spontaneous abortion patients.
The distribution of abnormal embryonic karyotype is a major factor related to RSA and further studies are needed to elucidate the etiology of RSA in order to achieve more effective prevention and treatment.
Chinese single herbs and active ingredients for postmenopausal osteoporosis: From preclinical evidence to action mechanism.
This article reviews the experimental evidence of both in vitro and in vivo preclinical studies of the application of Chinese single herbs and active ingredients in postmenopausal osteoporosis and investigates the underlying mechanisms including osteoprotegerin/receptor activator of nuclear factor κB ligand (OPG/RANKL).
Traditional Chinese medicine for human papillomavirus (HPV) infections: A systematic review.
Traditional Chinese medicine improves clinical index in the treatment of cervical cancer and genital warts; the mechanisms behind the effectiveness might be the regulation of cell apoptosis, viral gene transcription and translation, cell signal transduction pathways, and immune function.
Heterozygous deletion of LRP5 gene in mice alters profile of immune cells and modulates differentiation of osteoblasts.
Heterozygous deletion of the LRP5 gene in mice could alter the profile of the immune cells, influence the balance of immune environment, and modulate bone homeostasis, which might present a potential mechanism to explore the Wnt signaling pathway in the modulation of theimmune system.
Oxidative stress in oocyte and embryo development: implications for in vitro systems.
The oxidative stress in folliculogenesis and embryo development is summarized and the multiple modifiable factors of the in vitro culture systems in relation to the ROS are discussed.
Distinct pattern of Th 17 / Treg cells in pregnant women with a history of unexplained recurrent spontaneous abortion
It is concluded that the decrease in Treg cells and levels of CTLA-4 and TGF-β1 and as well as the increase in levels of IL-6 and TNF-ɑ, and the Th17/Treg ratio at the maternal- Fetal interface might contribute to inappropriate maternal-fetal immune tolerance in URSA.