The muscarinic acetylcholine receptor subtype 1 (M1) receptors play an important role in cognition and memory, and are considered to be attractive targets for the development of novel medications to treat cognitive impairments seen in schizophrenia and Alzheimer's disease. Indeed, the M1 agonist xanomeline has been shown to produce beneficial cognitive… (More)
INTRODUCTION The invasive pneumococcal diseases (IPDs) caused by Streptococcus pneumoniae pose an enormous threat to children under 5 years of age. However, routine use of pneumococcal conjugate vaccines could aid in reducing the incidence of IPDs. The purpose of this clinical trial is to assess the non-inferiority of the investigational 13-valent… (More)
(2010). Distributed storage and querying techniques for a semantic web of scientific workflow provenance. (2010a). Camera 2.0: A data-centric metagenomics community infrastructure driven by scientific workflows. (2004a). A framework for the design and reuse of grid workflows.