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Immune Checkpoint in Glioblastoma: Promising and Challenging
Glioblastoma (GBM) is a severe malignant brain cancer with poor overall survival. Conventional intervention remains dismal to prevent recurrence and deterioration of GBM cell. Recent years have… Expand
pH-sensitive docetaxel-loaded D-α-tocopheryl polyethylene glycol succinate-poly(β-amino ester) copolymer nanoparticles for overcoming multidrug resistance.
Multidrug resistance (MDR) is one of the major obstacles to successful chemotherapy. Overexpression of drug efflux transporters such as P-glycoprotein (P-gp) is an important factor responsible for… Expand
Discovery of Mosquito Saliva MicroRNAs during CHIKV Infection
- Payal D Maharaj, S. Widen, Jing Huang, T. Wood, S. Thangamani
- Biology, Medicine
- PLoS neglected tropical diseases
- 1 January 2015
Mosquito borne pathogens are transmitted to humans via saliva during blood feeding. Mosquito saliva is a complex concoction of many secretory factors that modulate the feeding foci to enhance… Expand
Molecular Characterization and Phylogenetic Analysis of New Variants of the Porcine Epidemic Diarrhea Virus in Gansu, China in 2012
Between January 2012 and March 2012, the infection rates of porcine epidemic diarrhea virus (PEDV) increased substantially in vaccinated swine herds in many porcine farms in Gansu Province, China.… Expand
Attentional Selection and Suppression in Children With Attention-Deficit/Hyperactivity Disorder.
- E. Wang, L. Sun, +9 authors Yan Song
- Psychology, Medicine
- Biological psychiatry. Cognitive neuroscience and…
- 1 July 2016
BACKGROUND Attention-deficit/hyperactivity disorder (ADHD) is a prevalent neurodevelopmental disorder with prominent impairments in directing and sustaining attention. The aim of this study was to… Expand
Predicting perceptual learning from higher-order cortical processing
Visual perceptual learning has been shown to be highly specific to the retinotopic location and attributes of the trained stimulus. Recent psychophysical studies suggest that these specificities,… Expand
Quantitative comparison of the hemodynamic activation elicited by cardinal and oblique gratings with functional near-infrared spectroscopy
Evidence has been accumulated for over a century indicating that the visual system of humans and many animals is more sensitive to contour stimulation at vertical or horizontal orientations than… Expand
Lowly pathogenic avian influenza (H9N2) infection in Plateau pika (Ochotona curzoniae), Qinghai Lake, China.
Avian influenza viruses (AIVs) are globally important contagions. Several domestic mammals can be infected with AIVs and may play important roles in the adaptation and transmission of these viruses… Expand
Identification of interferon-inducible genes as diagnostic biomarker for systemic lupus erythematosus
The identification of biomarkers helps to perform early diagnosis, thus benefits the outcome of patients with systemic lupus erythematosus (SLE), in which delayed treatment has been proposed as an… Expand
Nanomaterial Preparation by Extrusion through Nanoporous Membranes.
Template synthesis represents an important class of nanofabrication methods. Herein, recent advances in nanomaterial preparation by extrusion through nanoporous membranes that preserve the template… Expand