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In web search, recency ranking refers to ranking documents by relevance which takes freshness into account. In this paper, we propose a retrieval system which automatically detects and responds to recency sensitive queries. The system detects recency sensitive queries using a high precision classifier. The system responds to recency sensitive queries by(More)
Realtime web search refers to the retrieval of very fresh content which is in high demand. An effective portal web search engine must support a variety of search needs, including realtime web search. However, supporting realtime web search introduces two challenges not encountered in non-realtime web search: quickly crawling relevant content and ranking(More)
Language Modeling (LM) has been successfully applied to Information Retrieval (IR). However, most of the existing LM approaches only rely on term occurrences in documents, queries and document collections. In traditional unigram based models, terms (or words) are usually considered to be independent. In some recent studies, dependence models have been(More)
Photoreceptor and cone cells in the Drosophila eye are recruited following activation of the epidermal growth factor receptor (EGFR) pathway. We have identified echinoid (ed) as a novel putative cell adhesion molecule that negatively regulates EGFR signaling. The ed mutant phenotype is associated with extra photoreceptor and cone cells. Conversely, ectopic(More)
Rodent homologues of two candidate dyslexia susceptibility genes, Kiaa0319 and Dcdc2, have been shown to play roles in neuronal migration in developing cerebral neocortex. This functional role is consistent with the hypothesis that dyslexia susceptibility is increased by interference with normal neural development. In this study we report that in utero RNA(More)
Induction of CYP2E1 by ethanol is one of the central pathways by which ethanol generates a state of oxidative stress in hepatocytes. To study the biochemical and toxicological actions of CYP2E1, our laboratory established HepG2 cell lines which constitutively overexpress CYP2E1 and characterized these cells with respect to ethanol toxicity. Addition of(More)
User query is an element that specifies an information need, but it is not the only one. Studies in literature have found many contextual factors that strongly influence the interpretation of a query. Recent studies have tried to consider the user's interests by creating a user profile. However, a single profile for a user may not be sufficient for a(More)
High-intensity focused ultrasound (HIFU) is a noninvasive treatment that induces complete coagulative necrosis of a tumour at depth through the intact skin. This study was to explore the possibility of using HIFU for the treatment of patients with localised breast cancer in a controlled clinical trial. A total of 48 women with biopsy-proven breast cancer(More)
Altering voltage-gated ion channel currents, by changing channel number or voltage-dependent kinetics, regulates the propagation of action potentials along the plasma membrane of individual cells and from one cell to its neighbors. Functional increases in the number of cardiac sodium channels (Na(V)1.5) at the myocardial sarcolemma are accomplished by the(More)