Jindra Vrzalova

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BACKGROUND Abnormal postprandial elevation of plasma glucose and lipids plays an important role in the pathogenesis of diabetes and strongly predicts cardiovascular mortality. In patients suffering from type 2 diabetes (T2D) postprandial state is associated with oxidative stress, cardiovascular risk and, probably, with impairment of both secretion and the(More)
BACKGROUND The intake of meat, particularly processed meat, is a dietary risk factor for diabetes. Meat intake impairs insulin sensitivity and leads to increased oxidative stress. However, its effect on postprandial gastrointestinal hormone (GIH) secretion is unclear. We aimed to investigate the acute effects of two standardized isocaloric meals: a(More)
Purpose. To determine the intraocular levels of growth factors and cytokines in patients with various degrees of severity of proliferative diabetic retinopathy (PDR) using multiplex xMAP technology. Methods. A prospective cohort study of 61 eyes from 56 patients who were divided into 3 groups based on the severity of PDR. Patients in group number 1 are(More)
The incidence of melanomas has been increasing over the past decades. According to WHO statistics 132 000 mela-noma skin cancers occur currently each year globally, as an ozone levels have been depleting, the next incidence increase of melanomas is estimated. The melanoma is highly metabolically active tumor that releases number of molecules. This study(More)
Scientific objectives Monitoring changes in the levels of biomarkers PSA, % freePSA, [-2] proPSA and calculation of PHI in the diagnostic algorithm of early prostate cancer. in Pilsen examined sera of 76 patients from the Urology department of the University Hospital with suspected prostate cancer who have undergone TRUS biopsy. We assessed the levels of(More)
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