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Protective effect of porphyra-334 on UVA-induced photoaging in human skin fibroblasts
The results suggest that porphyra-334 has various applications in cosmetics and toiletries because of its anti-photoaging activities and may serve as a novel anti-aging agent. Expand
Enzyme delivery using the 30Kc19 protein and human serum albumin nanoparticles.
The 30Kc19-HSA protein nanoparticles had negligible toxicity to animal cells and exhibited enhanced cellular uptake and intracellular stability of β-galactosidase in HeLa and HEK293 cells when compared with those of HSA nanoparticles. Expand
Spray-dried conjugated linoleic acid encapsulated with Maillard reaction products of whey proteins and maltodextrin
Encapsulation performance of Maillard reaction products (MRPs) produced by whey proteins and maltodextrin were examined for microencapsulation of conjugated linoleic acid (CLA) using spray-drying.Expand
Mechanism of Inhibition of HepG2 Cell Proliferation by a Glycoprotein from Hizikia fusiformis
Hizikia fusiformis, a brown alga that is widely consumed in Korea, Japan, and China, possesses a number of potentially beneficial compounds, including antioxidants and anticoagulants, which might be useful in the treatment of liver cancer. Expand
Robust size control of bovine serum albumin (BSA) nanoparticles by intermittent addition of a desolvating agent and the particle formation mechanism.
It is demonstrated that the intermittent addition of a desolvating agent can improve reproducibility in the preparation of polymeric bovine serum albumin (BSA) nanoparticles and, using this modification, BSA nanoparticles of controlled size can be manufactured with narrow particle size distributions. Expand
Nrf2 and NF-κB Signaling Pathways Contribute to Porphyra-334-Mediated Inhibition of UVA-Induced Inflammation in Skin Fibroblasts
The results show that the antioxidant effect of porphyra-334 is due to the direct scavenging of oxidative stress and its inhibitory effects on NF-κB-dependent inflammatory genes, such as IL-6 and TNF-κ. Expand
α-Galactosidase delivery using 30Kc19-human serum albumin nanoparticles for effective treatment of Fabry disease
Protein nanoparticles using human serum albumin (HSA) and 30Kc19 protein, originating from silkworm, were used to enhance the delivery and intracellular α-galactosidase stability and showed enhanced globotriaosylceramide degradation in Fabry patients’ fibroblasts. Expand
Activation of the mTOR signaling pathway in breast cancer MCF-7 cells by a peptide derived from Porphyra yezoensis
The present study investigated mTOR pathway activation in MCF-7 cells treated with 500 ng PPY for 24 h by assessing LC3 as a monitor of autophagy, and observed that the p53/NF-κB and mTOR pathways were affected by PPY, which contributes to the understanding of the functional relationship between the Bcl-2 family and m TOR under apoptotic conditions in MCFs. Expand
Dynamic light scattering-based method to determine primary particle size of iron oxide nanoparticles in simulated gastrointestinal fluid.
Simple dynamic light scattering (DLS)-based methodologies were developed to determine primary particle size distribution of iron oxide particles in simulated gastrointestinal fluid and found that monodisperse particles were preferred by altering the pH to 7 and electrolyte elimination. Expand
Protein‐stabilizing and cell‐penetrating properties of α‐helix domain of 30Kc19 protein
Interestingly, 30Kc19α was shown to be responsible for both the protein‐stabilizing and cell‐penetrating properties of 30KC19 protein, which can be developed as a novel candidate for a therapeutic protein carrier into various cells and tissues. Expand