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Effect of green tea on blood glucose levels and serum proteomic patterns in diabetic (db/db) mice and on glucose metabolism in healthy humans
Evidence is provided that green tea has an antidiabetic effect on diabetes-induced modifications of the levels of several serum proteins, the first report demonstrating that a certain serum protein may be involved in the antihyperglycemic effect of green tea. Expand
Naringin-induced bone morphogenetic protein-2 expression via PI3K, Akt, c-Fos/c-Jun and AP-1 pathway in osteoblasts.
Evidence is provided that naringin increase BMP-2 expression and enhance osteogenic response via the phosphoinositide 3-kinase (PI3K), Akt, c-Fos/c-Jun and AP-1-dependent signaling pathway. Expand
Regulation and improvement of triterpene formation in plant cultured cells of Eriobotrya japonica Lindl.
Various different culture conditions for cultured cells of loquat to produce triterpenes, including illumination, carbon source, nutrient composition and culture system are investigated, finding that suspension cultures of Loquat cell could achieve high productivity as callus culture. Expand
Antiosteoporotic activity of Davallia formosana.
The results suggest that DFE may represent a useful remedy for the treatment of bone reabsorption diseases such as osteoporosis. Expand
Eriobotrya japonica improves hyperlipidemia and reverses insulin resistance in high‐fat‐fed mice
The findings provide a nutritional basis for the use of loquat as a functional food factor that may have benefits for the prevention of hyperlipidemia and diabetes. Expand
Identification of dendrobium species used for herbal medicines based on ribosomal DNA internal transcribed spacer sequence.
It is clear that D. catenatum is one of the most important sources of Dendrobii Herba (5 out of 21 samples), and an ITS1-5.8S-ITS2 sequence database of 196 Dend Robium species was constructed, and the database was employed to identify 21 herbal samples. Expand
Cytotoxic and antimalarial beta-carboline alkaloids from the roots of Eurycoma longifolia.
Three new beta-carboline alkaloids were isolated from the roots of Eurycoma longifolia and demonstrated significant cytotoxicity against human lung cancer and human breast cancer cell lines. Expand
Momordica charantia extract on insulin resistance and the skeletal muscle GLUT4 protein in fructose-fed rats.
This study demonstrates, for the first time, the beneficial effects of two different extracts of bitter melon on insulin resistance in rats fed a high-fructose diet thereby producing evidence of the role of changes in expression of PPAR gamma and GLUT4. Expand
Hispolon from Phellinus linteus has antiproliferative effects via MDM2-recruited ERK1/2 activity in breast and bladder cancer cells.
Hispolon ubiquitinates and downregulates MDM2 viaMDM2-recruited activated ERK1/2 and may be a potential anti-tumor agent in breast and bladder cancers. Expand
Traditional Chinese medicine herbal extracts of Cibotium barometz, Gentiana scabra, Dioscorea batatas, Cassia tora, and Taxillus chinensis inhibit SARS-CoV replication
  • C. Wen, L. Shyur, +6 authors N. Yang
  • Biology, Medicine
  • Journal of Traditional and Complementary Medicine
  • 1 October 2011
Six herbal extracts from Chinese medicinal herbs were found to be potent inhibitors of SARS-CoV at concentrations between 25 and 200μg/ml and suggest that these six herbal extracts may have potential as candidates for future development of anti-SARS therapeutics. Expand