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  • Shi Du Yan, Ann Marie Schmidt, +5 authors David Stern
  • Chemistry, Medicine
  • The Journal of biological chemistry
  • 1994 (First Publication: 1 April 1994)
  • Attack by reactive oxygen intermediates, common to many kinds of cell/tissue injury, has been implicated in the development of diabetic and other vascular diseases. Such oxygen-free radicals can beExpand
  • Sheng-xian Yuan, F. Yang, +11 authors W. Zhou
  • Biology, Medicine
  • Hepatology
  • 2012 (First Publication: 1 December 2012)
  • UNLABELLED Survival of patients with hepatocellular carcinoma (HCC) remains poor, which is largely attributed to active angiogenesis. However, the mechanisms underlying angiogenesis in HCC remain toExpand
  • Jin Zhang, Zhanguo Gao, Jun Yin, Michael J. Quon, Jianping Ye
  • Medicine, Biology
  • Journal of Biological Chemistry
  • 2008 (First Publication: 19 December 2008)
  • S6K1 (p70S6K) is a serine kinase downstream from Akt in the insulin signaling pathway that is involved in negative feedback regulation of insulin action. S6K1 is also activated by TNF-α, aExpand
  • Jonathan D. Violin, Lisa M. DiPilato, Necmettin Yildirim, Timothy C. Elston, Jin Zhang, Robert J Lefkowitz
  • Biology, Medicine
  • Journal of Biological Chemistry
  • 2008 (First Publication: 1 February 2008)
  • G protein-coupled receptor signaling is dynamically regulated by multiple feedback mechanisms, which rapidly attenuate signals elicited by ligand stimulation, causing desensitization. The individualExpand
  • Yuk Ming Dennis Lo, Lisa Y. S. Chan, +7 authors Dolly Poon Huang
  • Medicine
  • Cancer research
  • 1999 (First Publication: 1 November 1999)
  • Recently, cell-free EBV DNA has been detected in the plasma and serum of patients with nasopharyngeal carcinoma (NPC). We studied the relationship between plasma/serum EBV DNA and tumor recurrence.Expand