Jin Young Shin

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This study compared the contents of prosapogenin depending on the extracting conditions of Red ginseng to provide basic information for developing Red ginseng-based functional foods. The content of ginsenoside Rg3 reached their maximum value at 24 h of extraction, followed by 36 h and 72 h of extraction at 100°C.
The blood–brain barrier (BBB) protects the brain against potentially neurotoxic molecules in the circulation, and loss of its integrity may contribute to disease progression in neurodegenerative conditions. Recently, the active role of reactive astrocytes in BBB disruption has become evident in the inflamed brain. In the present study, we investigated(More)
BACKGROUND Increased fasting plasma glucose (FPG), which includes impaired fasting glucose (IFG), impaired glucose tolerance (IGT), and diabetes, is a risk factor for arterial stiffness. While IFG is widely accepted as a cardiovascular risk factor, recent studies have argued that subjects with high-normal glucose level were characterized by a high incidence(More)
A high serum uric acid (SUA) level is a known risk factor for cardiovascular disease. However, little is known about the relationship between arterial stiffness and uric acid in healthy subjects with a normal SUA level. We assessed whether a high-normal uric acid level increased arterial stiffness by measuring brachial-ankle pulse wave velocity (ba-PWV) in(More)
This study measures the effect of emissions from an airport on the air quality of surrounding neighborhoods. The ambient concentrations of benzene, toluene, ethylbenzene, and o-, m-, and p-xylene (BTEX) were measured using passive samplers at 15 households located close to the airport (indoor, outdoor, and personal), at the end of airport runways and an(More)
INTRODUCTION This study was to evaluate the in vivo distribution of intravenously transplanted bone marrow-derived mesenchymal stem cells (BMSCs) in an acute brain trauma model by (111)In-tropolone labeling. METHODS Rat BMSCs were labeled with 37 MBq (111)In-tropolone. Their labeling efficiency and in vitro retention rate were measured. The viability and(More)
Concentrations of selected heavy metals (Cd, Cr, Cu, Pb, Ni, Fe, and Zn), nutrients (NO (3) (-) and NH(3)), fecal coliform colonies, and other multiple physical-chemical parameters were measured seasonally from 12 locations in an urban New Jersey estuary between 1994 and 2008. Stepwise(More)
BACKGROUND We assessed the impact of vitamin D on hemoglobin levels in Korean adults, considering gender and menopausal status. METHODS We analyzed 2528 men and 3258 women divided into quartiles of vitamin D from the Fifth Korean National Health and Nutrition Examination Survey 2010. Anemia was defined as a hemoglobin level of <13 g/dl in men and <12 g/dl(More)
Current evidence suggests a central role for autophagy in Alzheimer disease (AD), and dysfunction in the autophagic system may lead to amyloid-β (Aβ) accumulation. Using in vitro and in vivo AD models, the present study investigated whether mesenchymal stem cells (MSCs) could enhance autophagy and thus exert a neuroprotective effect through modulation of Aβ(More)
BACKGROUND AIMS Because of their ability to differentiate and widespread availability, human mesenchymal stromal cells (hMSC) are often used as a clinical therapeutic tool. However, the factors that determine the quality and viability of hMSC are not well understood. METHODS We evaluated the viability of hMSC over time using flow cytometry analysis (FACS)(More)