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The receiver operating characteristic (ROC) curve, which is defined as a plot of test sensitivity as they coordinate versus its 1-specificity or false positive rate (FPR) as the x coordinate, is an effective method of evaluating the performance of diagnostic tests. The purpose of this article is to provide a nonmathematical introduction to ROC analysis.(More)
Fluorodeoxyglucose (FDG)-positron emission tomography (PET) is being used more and more to differentiate benign from malignant focal lesions and it has been shown to be more efficacious than conventional chest computed tomography (CT). However, FDG is not a cancer-specific agent, and false positive findings in benign diseases have been reported. Infectious(More)
The purpose of this study was to develop an automated scheme to facilitate detection of localized ground-glass opacity (GGO) in the lung at computed tomography (CT). Institutional review board approval and informed consent were not required. Two radiologists reviewed CT images from 14 patients (five men, nine women) who had lung cancer or metastasis and(More)
OBJECTIVE To determine the usefulness of a computer-aided diagnosis (CAD) system for the automated detection of lung nodules at low-dose CT. MATERIALS AND METHODS A CAD system developed for detecting lung nodules was used to process the data provided by 50 consecutive low-dose CT scans. The results of an initial report, a second look review by two chest(More)
In lung cancer screening, benign and malignant nodules can be classified through nodule growth assessment by the registration and, then, subtraction between follow-up computed tomography scans. During the registration, the volume of nodule regions in the floating image should be preserved, whereas the volume of other regions in the floating image should be(More)
As the detection and characterization of lung nodules are of paramount importance in thoracic radiology, various tools for making a computer-aided diagnosis (CAD) have been developed to improve the diagnostic performance of radiologists in clinical practice. Numerous studies over the years have shown that the CAD system can effectively help readers identify(More)
PURPOSE To compare the MR signal intensity patterns and enhancement pattern of intracranial tuberculomas with their histopathologic features. METHODS MR images of six patients with surgically proved intracranial tuberculoma were reviewed retrospectively and were compared with histologic findings of the resected specimen. Detailed histologic examination(More)
A computational method was developed for the measurement of breast density using chest computed tomography (CT) images and the correlation between that and mammographic density. Sixty-nine asymptomatic Asian women (138 breasts) were studied. With the marked lung area and pectoralis muscle line in a template slice, demons algorithm was applied to the(More)
iven the increasing resolution of modern CT scanners, and the requirements for large-scale lung-screening examinations and diagnostic studies, there is an increased need for the accurate and reproducible analysis of the large numbers of images. Nodule detection is one of the main challenges of CT imaging, as they can be missed due to their small size, low(More)
OBJECTIVE Bronchogenic carcinoma can mimic or be masked by pulmonary tuberculosis (TB), and the aim of this study was to describe the radiologic findings and clinical significance of bronchogenic carcinoma and pulmonary TB which coexist in the same lobe. MATERIALS AND METHODS The findings of 51 patients (48 males and three females, aged 48-79 years) in(More)