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Cloud Computing has been envisioned as the next-generation architecture of IT Enterprise. It moves the application software and databases to the centralized large data centers, where the management of the data and services may not be fully trustworthy. This unique paradigm brings about many new security challenges, which have not been well understood. This(More)
Cloud Computing has been envisioned as the next-generation architecture of IT Enterprise. It moves the application software and databases to the centralized large data centers, where the management of the data and services may not be fully trustworthy. This unique paradigm brings about many new security challenges, which have not been well understood. This(More)
As Cloud Computing becomes prevalent, sensitive information are being increasingly centralized into the cloud. For the protection of data privacy, sensitive data has to be encrypted before outsourcing, which makes effective data utilization a very challenging task. Although traditional searchable encryption schemes allow users to securely search over(More)
Data deduplication is a technique for eliminating duplicate copies of data, and has been widely used in cloud storage to reduce storage space and upload bandwidth. Promising as it is, an arising challenge is to perform secure deduplication in cloud storage. Although convergent encryption has been extensively adopted for secure deduplication, a critical(More)
—As Cloud Computing becomes prevalent, more and more sensitive information are being centralized into the cloud. For the protection of data privacy, sensitive data usually have to be encrypted before outsourcing, which makes effective data utilization a very challenging task. Although traditional searchable encryption schemes allow a user to securely search(More)
Epidemiologic studies have evaluated the association between KRAS mutations and resistance to the treatment of epidermal growth factor receptor (EGFR) tyrosine-kinase inhibitors (TKIs) in patients with non-small cell lung cancer (NSCLC). However, results were inconclusive. To derive a more precise estimation of the relationship, we performed this(More)
PURPOSE Cediranib is a highly potent inhibitor of vascular endothelial growth factor (VEGF) signaling with activity against all three VEGF receptors. HORIZON II [Cediranib (AZD2171, RECENTIN) in Addition to Chemotherapy Versus Placebo Plus Chemotherapy in Patients With Untreated Metastatic Colorectal Cancer] assessed infusional fluorouracil, leucovorin, and(More)
PURPOSE In Asian countries, paclitaxel once per week is used as second-line treatment in advanced gastric cancer, including human epidermal growth factor receptor 2 (HER2) -positive tumors. The role of anti-HER2 agents, including lapatinib, in this setting and population is unclear. PATIENTS AND METHODS TyTAN was a two-part, parallel-group, phase III(More)
Agmatine (decarboxylated arginine) has been known as a natural product for over 100 years, but its biosynthesis in humans was left unexplored owing to long-standing controversy. Only recently has the demonstration of agmatine biosynthesis in mammals revived research, indicating its exceptional modulatory action at multiple molecular targets, including(More)
OBJECTIVES To characterize the hemodynamics comparing thulium laser vaporesection of the prostate with traditional transurethral resection of the prostate. METHODS A total of 80 consecutive patients with benign prostatic hyperplasia were randomly assigned into the thulium laser vaporesection of the prostate group or transurethral resection of the prostate(More)