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BACKGROUND Inflammation plays a prominent role in the etiology of the early recurrence of atrial fibrillation (ERAF). We prospectively compared the proportion of ERAF and time-course patterns of biomarkers between radiofrequency (RF) and cryoballoon (CB) ablation. METHODSANDRESULTS We enrolled 82 consecutive paroxysmal AF patients undergoing pulmonary(More)
BACKGROUND Periesophageal vagal nerve injury is recognized as a rare complication in atrial fibrillation ablation procedures. We investigated the factors associated with the occurrence of symptomatic periesophageal vagal nerve injury after pulmonary vein antrum isolation. METHODS AND RESULTS Overall, 535 consecutive patients who underwent sole pulmonary(More)
BACKGROUND Radiofrequency applications around pulmonary vein (PV) ostia often induce vagal reflexes. OBJECTIVE This study aimed to evaluate the impact of the order of the targeted PV on the vagal response during second-generation cryoballoon ablation. METHODS Eighty-one consecutive paroxysmal atrial fibrillation (AF) patients undergoing cryoballoon(More)
BACKGROUND Early recurrence of atrial fibrillation (ERAF) is common after pulmonary vein antrum isolation (PVAI); however, the definition, study population, and lesion set are not uniform in prior studies. We examined ERAF for paroxysmal AF while complying with the definition in the latest guidelines. METHODSANDRESULTS We included 471 patients undergoing(More)
BACKGROUND Left phrenic nerve injury (PNI) can occur during cryoballoon ablation of the left pulmonary veins (PVs). This study aimed to evaluate the feasibility of monitoring the bilateral phrenic nerve function during cryoballoon ablation of atrial fibrillation (AF). METHODS Fifty consecutive paroxysmal AF patients undergoing cryoballoon ablation using(More)
BACKGROUND Phrenic nerve injury (PNI) is recognized as an important complication during atrial fibrillation ablation. This study aimed to investigate the incidence and outcome of PNI during superior vena cava isolation (SVCI) and circumferential pulmonary vein isolation (CPVI) using radiofrequency (RF) energy and the factors associated with its occurrence.(More)
BACKGROUND Adenosine triphosphate (ATP) testing reveals dormant pulmonary vein (PV) conduction after electrical PV isolation (PVI). This study aimed to evaluate the incidence of latent PV conduction after cryothermal PVI. METHODS Fifty-four consecutive paroxysmal atrial fibrillation patients undergoing cryothermal PVI were prospectively enrolled. PVI was(More)
BACKGROUND Saline irrigation improved the safety of radiofrequency (RF) ablation, but the thermal feedback for energy titration is absent. OBJECTIVES To allow temperature-controlled irrigated ablation, a novel irrigated RF catheter was designed with a diamond-embedded tip (for rapid cooling) and 6 surface thermocouples to reflect tissue temperature.(More)
BACKGROUND Deep sedation or general anesthesia is generally used during atrial fibrillation (AF) ablation. The aim of this study was to report the safety and feasibility of minimal sedation during AF ablation. METHODS AND RESULTS One thousand and fifty-two AF ablation procedures in 819 patients (62 ± 11 years, 621 men, 506 paroxysmal) were included.(More)
BACKGROUND The utility of compound motor action potential (CMAP) monitoring for anticipating phrenic nerve injury (PNI) during cryoballoon ablation has been reported. We sought to compare two different CMAP recording techniques and evaluated the feasibility during pulmonary vein antrum isolation (PVAI) and superior vena cava isolation (SVCI) using(More)