Four cases of pleomorphic xanthoastrocytoma (PXA), a low-grade leptomeningeal glioma with a reported favorable prognosis affecting young patients, are reported together with a discussion and review of management and prognosis. A literature review has confirmed a favorable prognosis in at least 50% of patients with this disorder. Seventeen of 35 reported… (More)
The authors present a patient who developed an acute hemorrhage around a Silastic dural substitute 13 weeks after excision of a meningioma and implantation of the graft. The relevant literature is reviewed.
A retrospective survey has been carried out on 56 children with shunted hydrocephalus either with a primary idiopathic cause or as a result of a low spina bifida complex. In all 56 children, a separate reservoir has been inserted at some stage in the management of their hydrocephalus. There was no mortality. Morbidity was not increased from CSF infection or… (More)
A personal review and recollection of the development of paediatric neurosurgery, as seen from Edinburgh, on the occasion of the twenty-fifth anniversary of the foundation of the International Society for Pediatric Neurosurgery.
The case of a newborn boy with a congenital cystic neck mass causing respiratory distress is reported. This lesion extended from the submandibular region through a bone defect to the middle cranial fossa but remained totally extradural. There was no underlying brain abnormality. The cyst was composed mainly of mature neuroglial tissue, with some ependymal… (More)
A 5-year-old white boy presented with life-threatening haematemesis from spontaneous rupture of an aneurysm of the high cervical internal carotid artery (ICA). The haemorrhage was controlled by emergency trap ligation of the distal ICA in the neck. The child made an excellent recovery and 7 years later has no neurologic deficit other than an Horner's… (More)
Thirty two human tumours, mainly neurogenic, have been investigated for the presence of adenovirus-related RNA sequences. 3H-labelled tumour virus DNA probes derived from human adenoviruses types 2 and 12, bovine adenovirus type 3, and avian adenovirus CELO were hybridized in-situ on tumour kryostat sections under conditions that detect complementary RNA.… (More)
A case is described of an epidermal carcinoma developing at the site of a myelomeningocele in a 50-year-old man. As in the three other cases of this condition which have been reported, the patient died, which reinforces the suggestion that possible malignant changes, though rare, should be taken into account when considering closure of such dysraphic… (More)